Special Issue "Molecular Mechanisms of Immunity to Infectious Viruses"

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".

Deadline for manuscript submissions: 30 December 2023 | Viewed by 290

Special Issue Editors

Center of Basic Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou St., 11527 Athens, Greece
Interests: viral infections; epigenome architecture and function; inducible gene expression programs; genomics; evolution of cis-acting elements
School of Medicine, University of Patras, Rio, Greece
Interests: viral infections; immune cell biology; gene expression programs; epigenetics; chromatin architecture
Genetics Laboratory, Biotechnology Department, Agricultural University of Athens, Athens, Greece
Interests: functional role of long non-coding RNAs; stress mechanisms and homeostasis via nuclear receptors; computational and molecular virology under the prisms of genetics; computational biology; precision medicine
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Special Issue Information

Dear Colleagues, 

We are delighted to announce a Special Issue of Cells: "Molecular Mechanisms of Immunity to Infectious Viruses".

Viral infections dramatically impact human health and occasionally act as causal factors for morbidity and mortality among human populations that can lead to pandemic outbreaks. Immune responses are shaped as defense layers against viral life-cycle progression within human tissues. A hallmark of this function is the establishment of inducible expression programs. Much has been learned due to the advent of cell biology applications efficient in immunophenotyping and next-generation sequencing technologies, genomics applications, and computational biology tools applied to access the regulatory principles of gene expression, which can collectively illuminate the defense mechanisms that hosts utilize to combat viral infections. Advanced studies have characterized a plethora of cell types of the immune system and delineated diverse mechanistic principles, multiple layers of regulation, and cellular components, such as receptors, signal transduction cascades, transcriptional regulatory factors, chromatin complexes, and secreted effectors, committed in defense-specific responses at the cell- and tissue-level. Despite the essential knowledge that has emerged, it still remains challenging to comprehend how immune cells establish inducible gene-expression programs and shape efficient antiviral/defense responses within the heterogeneous 3D microenvironments of the human body. Hence, disentangling such perplexing phenomena is of paramount importance for an in-depth understanding of the mechanisms of human immunity, within and beyond the context of viral infections. 

For this Special Issue of Cells, research articles, research reports, and reviews focused on the molecular mechanisms of immunity to infectious viruses will be considered for publication.

Dr. Marios Agelopoulos
Dr. Tassos Georgakopoulos
Dr. Dimitrios Vlachakis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • viral infections
  • immune cell biology
  • gene expression programs
  • epigenetics
  • chromatin architecture
  • cis-regulatory elements
  • functional genomics
  • computational biology applications

Published Papers

This special issue is now open for submission.
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