Molecular and Cellular Mechanisms on Plant Polyphenols

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Plant, Algae and Fungi Cell Biology".

Deadline for manuscript submissions: 20 August 2024 | Viewed by 230

Special Issue Editors

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Guest Editor
Department of Biomedical, Experimental and Clinical Sciences “Mario Serio", University of Florence, Viale Morgagni 50, 50134 Florence, Italy
Interests: amyloid; cytotoxicity; inflammation; polyphenols
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Viale Morgagni 50, 50134 Florence, Italy
Interests: amyloid aggregation; autophagy; natural polyphenols; neurodegenerative diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The increasing extension in life expectancy is accompanied by a progressively greater rate of chronic diseases, most of which are still waiting for effective therapies. The claimed health benefits of the Mediterranean and Asian diets have been confirmed in many clinical trials and epidemiological surveys. These diets can be traced back to the presence of significant amounts of naturally occurring bioactive molecules as secondary metabolites that are naturally synthesized in plants, structurally optimized by evolution toward particular biological functions, including the regulation of endogenous defense mechanisms and interaction with other organisms. Among the enormous quantities of these bioactive molecules, polyphenols have shown a pleiotropic behavior on key proteins that act as regulators of the complex cell homeostatic systems including metabolic and redox balance, proteostasis, and inflammatory response. This Special Issue aims to bring researchers together in an open forum where researchers can share the innovative results of their investigations both in the form of original research or review papers in order to provide an overview of the current knowledge in the myriad functions and mechanisms of dietary or non-dietary polyphenols and provide a rationale for the possible use of these substances, or their molecular scaffolds, as nutraceuticals or for new drugs design. At the same time, this open forum can provide the opportunity for new collaborations and interactions with the industrial world.

Dr. Monica Bucciantini
Dr. Manuela Leri
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • natural polyphenols
  • cell homeostasis
  • anti-oxidant
  • anti-inflammatory
  • health effects

Published Papers

This special issue is now open for submission.
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