Human Organoids: A New Frontier in Disease Modeling
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 47
Special Issue Editors
Interests: 3D skin organoids; fibrosis; myofibroblast; cellular senescence
Special Issue Information
Dear Colleagues,
Organoids—three-dimensional (3D) cultures derived from pluripotent, fetal, or adult stem cells—faithfully recapitulate key structural and functional features of native organs. Encompassing a wide spectrum of models, including cellular spheroids, reconstructed 3D tissues, and bioengineered organ-like systems, organoids offer unprecedented opportunities not only in regenerative medicine but also as in vitro platforms to study complex biological processes. Human organoids enable the exploration of otherwise inaccessible aspects of human development, overcoming challenges posed by limited tissue availability and ethical constraints.
This Special Issue highlights the rapidly evolving landscape of organoid technologies, which are emerging as transformative tools for modeling human development, physiology, and disease. We aim to showcase cutting-edge research that leverages human organoids for diverse applications, including regenerative medicine, embryonic development, host–pathogen interactions, high-throughput drug screening, therapeutic efficacy testing, and precision medicine. We particularly encourage submissions that employ organoid systems to elucidate disease mechanisms, identify novel therapeutic targets, and drive translational research.
Submissions are welcome across a broad range of organoid models and biological questions. This issue seeks to foster interdisciplinary dialog and spotlight innovations at the intersection of basic science, biotechnology, and clinical medicine in the organoid field.
Dr. Priyanka Verma
Dr. Umesh Kumar
Guest Editors
Manuscript Submission Information
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Keywords
- 3D organ culture
- embryonic stem cells
- induced pluripotent stem cells
- 3D bioprinting
- personalized medicine
- regenerative medicine
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