Molecular and Translational Advances in Metastatic Breast Cancer Research
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 15 May 2026 | Viewed by 10
Special Issue Editor
Interests: metastatic breast cancer; therapeutic resistance mechanisms; tumor microenvironment; cancer immunotherapy; targeted therapy; translational oncology; cancer stem cells; molecular oncology; tumor heterogeneity; precision medicine.
Special Issue Information
Dear Colleagues,
Metastatic breast cancer (MBC) represents the most lethal stage of breast malignancy and remains a formidable clinical challenge, accounting for the vast majority of breast cancer-related deaths globally. Despite significant advances in early detection and localized disease management, metastatic disease remains largely incurable, necessitating sustained research efforts to elucidate its underlying biology and identify more effective therapeutic strategies.
This Special Issue of Cells will highlight recent progress in the mechanistic understanding, molecular characterization, and therapeutic targeting of MBC. We invite submissions that explore novel insights into the molecular and cellular drivers of metastasis, including epithelial–mesenchymal transition, tumor heterogeneity, dormancy, immune evasion, and organotropism. Additionally, we welcome research addressing resistance to systemic therapies, including endocrine therapy, chemotherapy, targeted agents, and immunotherapies.
Studies incorporating cutting-edge technologies such as spatial transcriptomics, single-cell multiomics, liquid biopsy platforms, and patient-derived models are of particular interest. Clinical and translational research that bridges basic discoveries and therapeutic applications is especially encouraged. By gathering diverse perspectives and methodologies, this Special Issue will contribute to the development of more effective and durable interventions for patients with metastatic breast cancer.
Dr. Sravani Ramisetty
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metastatic breast cancer
- tumor microenvironment
- therapeutic resistance
- immunotherapy
- targeted therapy
- cancer biomarkers
- personalized medicine
- translational oncology
- circulating tumor cells
- molecular mechanisms of metastasis
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