Cellular and Molecular Mechanisms of Cardiomyopathy
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 30 March 2026 | Viewed by 36
Special Issue Editors
2. Veneto Institute of Moelcular Madicine, Via Orus 2, 35129 Padova, Italy
Interests: disease mechanisms in genetic and acquired cardiomyopathies; disease mechanisms in Amyotrophic Lateral Sclerosis; autonomic control of cardiac function in healthy and diseased hearts
Special Issues, Collections and Topics in MDPI journals
Interests: molecular mechanisms in heart failure; endothelial dysfunction; stroke with a focus on autophagy; Hippo pathway and mitochondrial dynamics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiomyopathies are a heterogeneous group of diseases which affect cardiac structure and function, and represent a major cause of heart failure, heart valve defects, cardiac arrest, and sudden cardiac death. While cardiomyopathies are often genetically determined, other etiological factors include high blood pressure, metabolic disorders, illicit drug use, chemotherapeutic agents, and coronary artery disease. Based on the morphological changes the heart undergoes, cardiomyopathies are classified into dilated cardiomyopathy, arrhythmogenic cardiomyopathy, and hypertrophic cardiomyopathy. Despite recent advancements in omics technologies and imaging techniques that have improved the management of patients with cardiomyopathies, many gaps in knowledge remain, especially those related to the cellular and molecular mechanisms underlying the development and progression of these diseases. Basic research has already demonstrated that numerous cellular processes, such as calcium handling, protein quality control, mitochondrial function, and neuro-cardiac communication are impaired in many forms of cardiomyopathy, with dramatic consequences for heart function. However, further studies are needed to better understand their specific contributions and to accelerate the translation of these findings into clinical practice. This Special Issue will focus on the characterization of novel cellular and molecular determinants involved in cardiomyopathies, with strong potential for prevention and therapy. We encourage the submission of original articles reporting studies conducted in validated animal models of genetic or acquired cardiomyopathy, as well as clinical evidence from patients and comprehensive review articles.
Dr. Zaglia Tania
Dr. Maurizio Forte
Guest Editors
Manuscript Submission Information
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Keywords
- genetic cardiomyopathies
- acquired cardiomyopathies
- cardiac arrhythmias
- disease mechanisms
- disease cause
- pathogenesis
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