The Highly Regulated Cellular System of Pancreatic β Cells: From Molecular Mechanisms to Physiology
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (25 July 2024) | Viewed by 3759
Special Issue Editor
Interests: neurotensin; beta cell insulin secreting cell; G protein coupled receptor; sortilin; receptors; insulin secretion; calcium signaling; potassium channel blockers; exocytosis; islets of langerhans
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue aims to unravel the latest discoveries and advancements in the field of pancreatic beta cells, including original research articles and comprehensive reviews. These cells are central to the control of carbohydrate homeostasis; as they synthesize and secrete insulin, they are responsible for maintaining blood sugar levels, and their dysfunction leads to pathologies such as diabetes. Studying them has opened up a whole new world of knowledge. On its subtle metabolic coupling machinery, between circulating glucose concentration and insulin secretion, the molecular machinery of the beta cell is regulated by a large number of highly robust signaling pathways. When studied in the context of type 1 or type 2 diabetes, this helps us to understand the mechanisms of autoimmune or metabolic diseases, respectively. For all these reasons, it will always be an exceptional research model that never ceases to surprise.
Dr. Thierry Coppola
Guest Editor
Manuscript Submission Information
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Keywords
- insulin secretion
- cell signaling
- receptor
- pharmacology
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