Special Issue "Metabolic Pathways and Redox Homeostasis in Cancer"
Deadline for manuscript submissions: closed (30 November 2020).
2. Centre Scientifique de Monaco (CSM), Monaco, 8 Quai Antoine Ier MC 98000 MONACO
Interests: cancer biology; hypoxia signaling; cancer metabolism; amino acid transporters; oxidative stress
Interests: cancer; redox regulation; amino acid transporters; ferroptosis; glutathione; metabolism; stress response pathways in cancer
Tumour metabolism is one of the oldest field in cancer biology, dating back to the seminal work of Otto Warburg in the 1920s. Great work in the late 1995–2005 in the hypoxia field, recently awarded by Nobel Prize, paved the way in the understanding how cancer cells adopt their metabolism, survive and even thrive in the conditions of low oxygen and nutrient supply. Metabolic plasticity of cancer cells, by their diversities and opportunities, continues to impress and inspire scientists all around the world in the last two decades. Even more complex and puzzling is the question of cancer redox homeostasis, where e.g., high level of reactive oxygen species (ROS) has been recognized as both pro-oncogenic (correlating with increased incidence of cancer) and anti-oncogenic (mechanism exploited by many chemotherapeutics and new form of cell death, like ferroptosis). Thus, further comprehensive research, as well as pre-clinical approaches, are required in order to maximally exploit these vulnerability points of the Biology/Physiology of Cancer.
This special issue on “Metabolic Pathways and Redox Homeostasis in Cancer” welcomes both original and review articles.
Dr. Jacques Pouyssegur
Dr. Milica VUCETIC
Dr. Fatima Mechta-Grigoriou
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Warburg effect
- fermentative glycolysis
- lactic acid
- cysteine homeostasis
- transsulfuration pathway
- cystine transport
- tumour microenvironment
- cancer-associated fibroblasts
- immune cells