Dynamics of Cancer: Complexity and Hierarchy on Cancer Cells and Tissues

Dear Colleagues,

Cancer is a complex disease, highly heterogeneous even for similar cells. Among other factors, tumor growth depends on dynamic interactions between cells and the continuously changing extracellular matrix microenvironment. It is still unknown why cancer therapies are more effective for some individuals and not for others. An interdisciplinary approach where physics, system dynamics, and biology will be integrated with traditional methods will tackle the challenge.

Generally, dynamical systems, such as cancerous ones, have structural (“hardware”) and functional (“software”) connotations that form ensembles of successfully interacting nested sets and subunits of variables and parameters forming different hierarchical dynamical states.

In the current Special Issue, novel topics, including cell and tissue biophysics and dynamics, biomechanics, nano-bio interactions, complexity, hierarchy, stability, chaos, the flow of information, cell memory, and novel cancer therapeutic and diagnostic methods at the nanoscale are welcome.

Dr. Evangelia Sarantopoulou
Dr. Angelo Ferraro
Guest Editors

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