Lipids and Small Metabolites in Cancer

Dear Colleagues,

Small molecule metabolites, such as amino acids, fatty acids, lipids, and numerous components of biochemical pathways, have emerged as a characteristic feature of tumor development. A wealth of omics data identified changes in the metabolome and the lipidome as a new hallmark of tumorigenesis. Understanding around pathological changes in the complex metabolome and lipidome has drastically improved. Cluster and pathway analyses of large datasets are inevitable bioinformatic tools to decode specific molecular patterns and their functions involved in the pathogenesis of tumors. The functional rewiring of disease-affected molecular cohorts can fuel complex multimodal therapeutic solutions with improved capacity to overcome resistance mechanisms.

This Special Issue, titled “Lipids and small metabolites in cancer”, welcomes all aspects of metabolome- and lipidome-related cancer research and review articles for a comprehensive view of this special topic based on omics screens, bioinformatics, targeted analyses, in vitro and in vivo experimental, or clinical results.

Dr. Zsolt Balogi
Dr. Laszlo Vigh
Guest Editors

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