Advances in Pancreatoduodenectomy

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Clinical Research of Cancer".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 913

Special Issue Editors


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Guest Editor
Department of Hepatobiliary and Pancreatic Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea
Interests: pancreatic cancer; pancreatectomy; laparoscopic; robotic

E-Mail Website
Guest Editor
Division of Hepatobiliary and Pancreas Surgery, Department of Surgery, Asan Medical Center, Ulsan University, Seoul, Republic of Korea
Interests: pancreatic surgery; robotic; pancreatic cancer; biliary cancer

Special Issue Information

Dear Colleagues,

In the past, pancreatoduodenectomy (PD) was once regarded as a surgical procedure to be avoided because of high morbidity and mortality rates. However, with advances in surgical experiences, techniques, profound anatomy knowledge, and the quality of perioperative management, PD is gold-standard in treating periampullary pathological lesions. In addition, the minimally invasive surgical approach, laparoscopic or robotic, has recently became one a hot topic in dealing with advances in PD.

I am very excited to invite you to contribute your expertise and insights to this groundbreaking compilation. This Special Issue aims to provide a comprehensive overview of recent advances, innovations, and breakthroughs in the field of pancreatoduodenectomy. We seek to explore the latest surgical techniques, technological advancements, perioperative management strategies, and outcomes research related to this critical aspect of cancer treatment. This Special Issue welcomes reviews, as well as original research articles, by August 15, 2024.

Prof. Dr. Chang Moo Kang
Prof. Dr. Jae Hoon Lee
Guest Editors

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Keywords

  • surgical innovations and techniques in pancreatoduodenectomy
  • surgical anatomy to understand pancreatoduodenectomy
  • advances in preoperative imaging and planning
  • perioperative care and complications management
  • oncologic outcomes and long-term survival studies
  • multidisciplinary approaches to enhance patient outcomes
  • emerging technologies and their impact on surgical precision

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Published Papers (1 paper)

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Review

10 pages, 247 KiB  
Review
Technical Feasibility of Microwave Ablation in Pancreatic Tumors: A Scoping Review of Procedural Efficacy and Safety
by Daniela Tabacelia, Carlos Robles-Medranda, Artsiom Klimko, Stephen P. Pereira, Peter Vilmann, Rogier P. Voermans, Adrian Săftoiu, Cristian George Tieranu and Cezar Stroescu
Cancers 2025, 17(7), 1197; https://doi.org/10.3390/cancers17071197 - 31 Mar 2025
Viewed by 382
Abstract
Background/Objectives: Pancreatic cancer remains one of the most aggressive and lethal malignancies, with limited effective treatment options for advanced stages. Microwave Ablation (MWA) has emerged as a minimally invasive therapeutic modality, offering potential benefits in tumor control. This review aims to critically assess [...] Read more.
Background/Objectives: Pancreatic cancer remains one of the most aggressive and lethal malignancies, with limited effective treatment options for advanced stages. Microwave Ablation (MWA) has emerged as a minimally invasive therapeutic modality, offering potential benefits in tumor control. This review aims to critically assess the safety and efficacy of MWA in the treatment of pancreatic cancer, focusing on its application in various pancreatic lesions. Methods: We systematically reviewed studies published between 2010 and 2023 that evaluated the use of MWA in pancreatic tumors, including locally advanced pancreatic cancer (LAPC), pancreatic neuroendocrine tumors (PNETs), and pancreatic metastases from renal cell carcinoma (RCC). Due to limited data on survival rates and long-term outcomes, our analysis concentrated primarily on the technical aspects and immediate procedural outcomes of MWA. Results: MWA was technically feasible in all cases. The overall complication rate was approximately 16.7% (nine patients), with higher incidences in tumors located in the pancreatic head. Reported complications included pancreatitis and pseudocyst formation. Procedural parameters varied, with applied energy ranging from 20 to 80 watts and ablation times between 2 to 15 min, depending on the microwave generator type and approach (percutaneous, intraoperative or endoscopic). All cases demonstrated effective necrosis of the target tissue, and several studies reported notable tumor size reductions, averaging up to 70%. Conclusions: MWA shows promise as a therapeutic option for pancreatic cancer, achieving high technical success rates and significant tumor reductions. However, the procedure is associated with a moderate complication rate, particularly in tumors located in the pancreatic head. Full article
(This article belongs to the Special Issue Advances in Pancreatoduodenectomy)
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