Special Issue "Screening and Genetic Characterization of Colorectal Cancer: A Multi-Step Approach"
Deadline for manuscript submissions: closed (30 June 2021).
Interests: Colorectal cancer; screening; clinical diagnosis; endoscopic imagining and (endoscopic) treatment; Clinical biomarkers of colorectal cancer; Inflammatory bowel disease and colorectal cancer
2. Candiolo Cancer Institute, FPO–IRCCS, 10060 Candiolo (TO), Italy
Interests: Genetics; Liquid Biopsy; Tumour Heterogeneity, Clonal Evolution; Bioinformatics; Colorectal Cancers
Colorectal cancer (CRC) is a largely preventable genetic disease, with well-established population-based organized screening programs and structured opportunistic screening in many countries across the world. Despite strong evidence that screening can reduce CRC incidence and mortality, wide variation still exists in the status, strategy, and effectiveness of the implementation of CRC screening efforts worldwide. When the tumor is identified, different advanced genetic approaches can be applied for its characterization. These approaches are relevant for patient stratification and the guidance of therapy in the precision oncology era. However, economic resources, healthcare structure, and infrastructure vary in their support of screening and precision oncology, guided by the advanced genetic characterization of the tumor. In addition, the COVID-19 pandemic has had a significant impact on screening and can enhance existing disparities. Many CRC screening and advanced genetic approaches that depend on research activities have been reduced or temporarily shut down during the pandemic, leading to a significant increase in cancer incidence and treatment delays. Because of the unknown timeline of the pandemic, this disruption may, in turn, decrease patient motivation to participate in screening or therapy.
This Special Issue presents a brief overview of CRC burden and the activity of genetic characterization, with a particular focus on challenges in the post-COVID-19 world. We address current trends in CRC screening/advanced genetic characterization and propose solutions to potential barriers.
Dr. Giovanni Crisafulli
Dr. Silvia Sanduleanu
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- colorectal cancer