The Role of Regulatory Non-Coding RNA in Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: closed (28 February 2025) | Viewed by 2001
Special Issue Editors
Interests: tumor biology; melanoma; skin cancers; photobiology; photochemistry
Special Issues, Collections and Topics in MDPI journals
Interests: melanoma; melanin biochemistry; skin pigmentation; melanin chemiexcitation; human genetics; environmental carcinogenicity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Although initially presumed to be non-functional, numerous studies in the past decade have established the indispensable functions of non-coding RNAs (ncRNAs), including in chromatin remodeling and transcriptional and post-transcriptional regulation. In cancer, some types of ncRNA have been implicated in events of initiation and progression. These include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), small interfering RNAs (siRNAs), PIWI-interacting RNAs, small nucleolar RNAs (snoRNAs), and sno-derived RNAs. Most studies discuss the involvement of miRNAs, siRNAs, and lncRNAs in different cancers, but other ncRNA types are also supposed to make significant contributions to carcinogenesis.
Since ncRNAs are critical in cancer development and metastasis, this Special Issue will not only describe the novel ncRNAs but also the unexplored mechanisms by which these ncRNAs regulate distinct aspects of carcinogenesis. This Special Issue will also focus on the therapeutic targeting of these ncRNAs in order to develop and optimize anticancer strategies. Moreover, this Special Issue will discuss whether the specific ncRNAs have tissue and/or cancer type-specific roles and regulation.
Dr. Jyoti Srivastava
Dr. Sanjay Premi
Guest Editors
Manuscript Submission Information
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Keywords
- cancer initiation
- cancer progression
- metastasis
- ncRNAs
- miRNAs
- lncRNAs
- gene regulation
- chromatin remodeling
- targeted therapeutics
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