Brain Cancer Stem Cells in Children and Adults
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: closed (1 March 2024) | Viewed by 3049
Special Issue Editor
Special Issue Information
Dear Colleagues,
Brain tumors can occur at any age and represent some of the most malignant cancers in both children and adults. Current standard therapies target the majority of brain tumor cells but do not adequately eradicate the cancer stem cell populations. Cancer stem cells are defined as tumor-initiating cells that possess self-renewal and differentiation properties similar to normal stem cells, with additional features of being highly tumorigenic and giving rise to a heterogeneous population of cells that comprise the tumor mass. Unless these brain cancer stem cells are eliminated, the possibility of a cancer cure is unlikely.
In this Special Issue of Cancers, our objective is to gather a collection of reviews and original research articles that cover the basic, translational, and/or clinical research topics which contribute to our understanding of the brain cancer stem cell biology and development of new therapeutic strategies on targeting cancer stem cells in pediatric and adult brain tumors.
Dr. Jia Shen
Guest Editor
Manuscript Submission Information
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Keywords
- brain cancer stem cell characterization
- signaling pathways
- tumor microenvironment
- therapy resistance
- novel therapeutics
- clinical relevance