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Health Equity and Clinical Outcomes in Hepatocellular Carcinoma

A Special Issue of Cancers (ISSN 2072-6694) belonging to the section "Clinical Research in Cancer".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 219

Editors


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Guest Editor
Gastroenterology Unit, Department of Internal Medicine, Azienda Ospedaliera Metropolitana IRCCS Policlinico San Martino, University of Genoa, Genoa, Italy
Interests: hepatocellular carcinoma; liver failure; portal hypertension; liver transplantation; material deprivation
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Guest Editor
Section of Digestive Diseases, Department of Internal Medicine, Yale Medical School, New Haven, CT, USA
Interests: hepatocellular carcinoma; epidemiology; genetic epidemiology; cancer screening; public policy; cost-effectiveness

Special Issue Information

Dear Colleagues,

As the third leading cause of cancer-related mortality, hepatocellular carcinoma remains a global health challenge. While the clinical management of hepatocellular carcinoma has advanced, significant disparities in patient outcomes persist, and emerging evidence indicates that clinical success is not only determined by tumor biology and therapeutic efficacy but is also profoundly shaped by social determinants of health.

This Special Issue, "Health Equity and Clinical Outcomes in Hepatocellular Carcinoma," aims to explore the multifaceted relationship between socioeconomic factors and clinical trajectories of patients at risk of and diagnosed with hepatocellular carcinoma. A primary focus of this collection is the impact of material deprivation and its root causes on the various stages of the care continuum. Specifically, we invite research addressing how individual, geographic, and policy factors influence hepatocellular carcinoma development, detection, treatment, and clinical outcomes, including the assessment of patient-reported outcomes.

We welcome original research, comprehensive reviews, and short communications that will provide insights and evidence-based strategies to mitigate these inequities. By characterizing "social risk phenotypes," we aim to inform targeted interventions and health system investments that ensure equitable care for all patients at risk of and diagnosed with hepatocellular carcinoma.

We look forward to receiving your contributions.

Kind regards,

Prof. Dr. Edoardo G. Giannini
Dr. Catherine Mezzacappa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hepatocellular carcinoma
  • health equity
  • material deprivation
  • social determinants of health
  • clinical outcomes
  • access to care
  • cancer staging
  • liver cancer disparities

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This special issue is now open for submission.
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