Translational Medicine in Gastroenteropancreatic Neuroendocrine Neoplasias

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Clinical Research of Cancer".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 161

Special Issue Editor


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Guest Editor
Department of Gastroenterology and Hepatology, Charité—Universitätsmedizin Berlin, Berlin, Germany
Interests: gastroenterology; hepatology; internal medicine; translational research; gastrointestinal oncology

Special Issue Information

Dear Colleagues,

Gastroenteropancreatic neuroendocrine tumors are a heterogeneous group of neoplasms arising from neuroendocrine cells of the gastrointestinal tract and pancreas characterized by variable growth kinetics and variable clinical courses in relation to their primary location and secretory activity. Therefore, based on their diverse biological behaviors, ranging from indolent to highly aggressive, they pose unique challenges in diagnosis and management. Despite their relative rarity, the incidence has been steadily increasing, attributed to improved diagnostic capabilities and heightened clinical awareness.

Recent advances have been mainly achieved in the field of basic sciences with the molecular profiling of tumor tissue at almost all multiomic levels. It is the aim of this review to elucidate current basic research for its applicability in the clinics. In this setting, it will be of utmost importance to show how this research will impact and improve the early detection and precise characterization of gastroenteropancreatic neuroendocrine neoplasias.

Therefore, this Special Issue aims at integrating cutting-edge technologies with an improved understanding of tumor biology, thereby moving the field closer to personalized medicine, offering hope for better prognostic stratification and tailored treatment strategies for patients with the neuroendocrine neoplasia.

Prof. Dr. Bertram Wiedenmann
Guest Editor

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Keywords

  • translational medicine
  • multiomics
  • improved diagnostics and therapy

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Published Papers

This special issue is now open for submission.
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