Therapy of Nasopharyngeal Carcinoma: Emphasizing Radiotherapy
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 135
Special Issue Editor
Interests: radiation oncology; NPC; head and neck cancer; radiotherapy; radioresistance; bi-omarkers; translational research
Special Issue Information
Dear Colleagues,
Nasopharyngeal carcinoma (NPC) is predominantly an Epstein–Barr virus (EBV)-driven malignancy, and radiotherapy remains the cornerstone of curative treatment; advances in IMRT and image-guided radiotherapy have substantially improved locoregional control. However, key challenges remain, including radioresistance, distant metastasis, treatment-related toxicities, and the need to individualize radiation dose and combined-modality strategies across heterogeneous risk groups. This Special Issue, “Therapy of Nasopharyngeal Carcinoma: Emphasizing Radiotherapy,” aims to showcase original research that improves the precision, effectiveness, and safety of radiotherapy for NPC while also addressing broader therapeutic strategies beyond radiotherapy.
We particularly welcome articles and reviews on target delineation and dose optimization; adaptive and precision radiotherapy; integration with systemic therapy (chemotherapy, immunotherapy, and targeted agents); multimodality strategies for distant metastasis and high-risk disease; imaging, radiomics, and biomarkers for risk stratification and response prediction; biological mechanisms of radioresistance and radiosensitization; toxicity mitigation and survivorship; management of recurrent NPC, including re-irradiation; management of metastatic and recurrent NPC, including salvage approaches; and prospective or real-world outcome studies. Translational, clinical, and technology-focused contributions are encouraged.
Prof. Yunfei Xia
Guest Editor
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Keywords
- nasopharyngeal carcinoma (NPC)
- radiotherapy
- IMRT
- adaptive radiotherapy
- dose optimization
- re-irradiation
- radioresistance
- radiomics
- biomarkers
- toxicity mitigation
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