Advances in Genetic and Molecular Approaches to Skin Cancer

Dear Colleagues,

Skin cancers are the most common malignancies in human. Genetic and molecular profiling has contributed to understanding the biology, improving the diagnosis and disease management in oncology and beyond. It refers to analysis of DNA, RNA, proteins and other compartments of the cell using techniques ranging from polymerase chain reaction (PCR) to multi-omics approaches. A PCR test can be run on tumor tissue to test for the BRAF V600 mutation in cutaneous melanoma, which would indicate tumor susceptibility for BRAF inhibitors; however, more advanced techniques are now used in tackling the mechanisms of resistance. Historically, genetic analysis was performed on tumor cells from metastases; however, not only detection of circulating of circulating tumor cells and DNA, but also molecular analysis is now possible. The field of genetic and molecular profiling is growing in many directions, including developing of new technologies, optimizing big-data interpretation, and understanding of clinical relevance and application.

For this Special Issue of Cancers, we welcome authors to submit original research articles or comprehensive reviews focusing on the development, research or clinical application of genetic and molecular approaches in skin cancers. We hope that such a collection of research will expand our knowledge on contemporary genetic and molecular profiling approaches and improve our understanding of their clinical implications.

Dr. Egle Ramelyte
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• genetic analysis
• multi-omics approaches
• skin cancer
• mutation
• epigenetic alteration
• proteomics