Clinical Expression and Progression of Huntington’s Disease
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".
Deadline for manuscript submissions: closed (5 October 2021) | Viewed by 11591
Special Issue Editor
Interests: alzheimer’s disease; traumatic brain injury; neuropathology; COVID-19
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, psychiatric, and cognitive deficits. Several studies have identified a large set of possible genetic modifiers, distinct from the HD locus itself, that could modify the clinical expression and progression of the disease. Current research seeks to uncover the exact molecular mechanisms driving the pathogenic cascade and clinical features of this complex disorder.
This Special Issue aims to gather cutting edge research on and expand our understanding of the mechanisms behind HD, which in turn open up novel therapeutic approaches for treating this currently incurable condition. Therefore, I invite authors to submit review articles, original research articles, or commentaries related to recent advances on the pathogenic process and clinical expression of HD.
Dr. Romina Vuono
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- Huntington’s disease
- genetic modifiers
- onset
- progression
- neurodegeneration
- therapy