Perioperative Neuroprotection: Mechanisms, Monitoring, and Clinical Strategies

A Special Issue of Brain Sciences (ISSN 2076-3425) belonging to the section "Neurosurgery and Neuroanatomy".

Deadline for manuscript submissions: 25 February 2027 | Viewed by 372

Editor


E-Mail Website
Guest Editor
Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Jacksonville, FL 32224 USA
Interests: neuroanesthesia; neuroprotection; perioperative neuroscience; brain injury; anesthetic neurotoxicity; awake neurosurgery; neurocritical care; translational neuroscience; perioperative brain health; neurosurgical analgesia

Special Issue Information

Dear Colleagues,

Protecting the brain during the perioperative period is an increasingly important challenge in modern medicine. Patients undergoing surgery are exposed to multiple risks in the perioperative period that affect neurological outcomes, including inflammation, hemodynamic instability, cerebral hypoperfusion, embolic phenomena, anesthetic effects, and postoperative complications. These risks are particularly high for older adults and for patients with a cardiovascular, neurologic, or cognitive vulnerability. This Special Issue will explore the emerging science of perioperative neuroprotection, from mechanisms of brain injury to practical strategies for prevention, monitoring, and recovery. This Special Issue aims to promote a deeper understanding of how perioperative care can be optimized to preserve neurologic function and improve patient-centered outcomes. The topics of interest include, but are not limited to, perioperative neuroinflammation, cerebral monitoring, biomarkers, postoperative delirium and neurocognitive disorders, stroke, anesthetic technique, and interventions aimed at improving brain health after surgery.

Dr. Shaun E. Gruenbaum
Guest Editor

Manuscript Submission Information

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Keywords

  • perioperative neuroprotection
  • surgery
  • brain health

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Published Papers

This special issue is now open for submission.
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