The Role of the Cerebellum in Motor and Non-motor Behaviours

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Sensory and Motor Neuroscience".

Deadline for manuscript submissions: closed (25 October 2024) | Viewed by 810

Special Issue Editor


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Guest Editor
Trinity College Institute of Neuroscience, Trinity Centre for Bioengineering and Department of Physiology, Trinity College Dublin, D02 PN40 Dublin, Ireland
Interests: motor learning; pain; neuromodulation; sensorimotor control
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Special Issue Information

Dear Colleagues,

The cerebellum has a diverse array of functions, far beyond its typical role in motor control. Underlying this range of behavioural functions is the presence of distinct cerebro-cerebellar circuits. The cerebellum is known to receive inputs from a wide range of cortical areas and send outputs to many cortical regions.  Further, while the cerebellum is known to contain distinct regions that connect with different cortical areas, much less is known about its functional arrangement relative to the cortex.

The focus of this Special Issue will be to elucidate how cerebro-cerebellar circuitry underlies different motor and non-motor behaviours. The Special Issue will cover topics, including animal models, imaging, electrical stimulation, non-invasive neuromodulation, electric field modelling, behaviours, and diseases.

Dr. Alice Witney
Guest Editor

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Keywords

  • cerebellum
  • motor
  • neuromodulation
  • motor learning
  • sensorimotor control

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Published Papers (1 paper)

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Research

28 pages, 13392 KiB  
Article
Optimising Electrode Montages in Conventional Transcranial Direct Current Stimulation and High-Definition Transcranial Direct Current Stimulation of the Cerebellum for Pain Modulation
by Adelais Farnell Sharp and Alice Witney
Brain Sci. 2025, 15(4), 344; https://doi.org/10.3390/brainsci15040344 - 27 Mar 2025
Viewed by 316
Abstract
The cerebellum is involved in pain processing and, therefore, an important target for non-invasive brain stimulation (NIBS) for analgesia. When targeting a brain region for NIBS, it can be difficult to ensure activation of only target regions. Optimal Montages for cerebellar stimulation for [...] Read more.
The cerebellum is involved in pain processing and, therefore, an important target for non-invasive brain stimulation (NIBS) for analgesia. When targeting a brain region for NIBS, it can be difficult to ensure activation of only target regions. Optimal Montages for cerebellar stimulation for pain modulation have not been established. This paper systematically examines cerebellar NIBS Montages by comparing simulated current flow models for targeted conventional cerebellar tDCS and focused high-definition 4 × 1 HD-tDCS, to examine the most effective Montage for targeting only the lobes of the cerebellum. The objective was to explore if slight variations in electrode placement and voltage could be producing confounding activations of other brain regions as shown by the Soterix® current modelling software (Ver. 2019). A left deltoid anode for right cerebellar lobe sponge (3 cm lateral to inion) produces the best targeting with conventional tDCS. For high-definition tDCS (HD-tDCS) a 4 × 1 array based on a 93-electrode EEG map, with the central electrode at PO10, and the array at O2, P8, Ex2, and Ex6, provided focal stimulation. Optimisation of NIBS must include an evaluation of electrode Montages and current flow modelling to determine which structures and pathways will be impacted by the neurostimulation. This approach is essential for future cerebellar NIBS experimental design and will facilitate comparative analysis across different protocols and optimise understanding of the role of the cerebellum in pain processing. Full article
(This article belongs to the Special Issue The Role of the Cerebellum in Motor and Non-motor Behaviours)
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