Polygenic, Epigenetic, and Multifactorial Determinants of the Brain, Behavior, and Health
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Behavioral Neuroscience".
Deadline for manuscript submissions: 25 April 2027 | Viewed by 7
Editors
2. Department of Medical Sciences and Public Health, Gdansk University of Physical Education and Sport, Kazimierza Gorskiego 1 St., 80-336 Gdansk, Poland
Interests: genetics; addiction; epigenetics; dopamine system; sport
Special Issues, Collections and Topics in MDPI journals
Interests: behavioral addiction; dependency; sport; dopamine; genetics; spirituality
Special Issue Information
Dear Colleagues,
The human brain and its associated behavioral and health outcomes arise from complex interactions among genetic, epigenetic, environmental, and lifestyle factors. Recent advances in genomics, epigenomics, neuroimaging, and computational neuroscience have highlighted the multifactorial nature of brain function and dysfunction, moving beyond single‑gene explanations toward integrated models of biological and behavioral regulation.
This Special Issue aims to explore the Polygenic, Epigenetic, and Multifactorial Determinants of the Brain, Behavior, and Health across the lifespan. We welcome original research articles, systematic reviews, and theoretical contributions investigating how genetic variation, epigenetic modifications, gene–environment interplay, and other biological or psychosocial factors shape neurological, psychiatric, cognitive, emotional, and behavioral phenotypes. Topics of interest include, but are not limited to, neurodevelopment, mental health, addiction, resilience, personality, cognition, physical activity, aging, and brain‑related somatic health outcomes. Studies involving human participants, animal models, or translational approaches are encouraged, particularly those integrating neuroscience with molecular biology, psychology, medicine, or public health.
Prof. Dr. Anna Grzywacz
Guest Editor
Dr. Remigiusz Recław
Guest Editor Assistant
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- polygenic risk
- epigenetics
- gene–environment interactions
- brain
- behavior
- mental health
- addiction
- personality
- cognition
- resilience
- physical activity
- aging
- neurodevelopment
- complex traits
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