Recent Advances in Glucose Sensors

A special issue of Biosensors (ISSN 2079-6374).

Deadline for manuscript submissions: closed (30 April 2014) | Viewed by 11912

Special Issue Editor


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Guest Editor
Department of Chemistry, University of Calgary, 2500 University Dr. N.W., Calgary, AB T2N 1N4, Canada
Interests: electrochemical sensors; glucose sensors; electrocatalysis; nanoparticles; nanotubes; fuel cells

Special Issue Information

Dear Colleagues,

A special issue of Biosensors, which is focused specifically on the topic of “Glucose Sensors”, will be published related to the massive challenge the world is facing in terms of diabetes. Diabetes is a chronic disease in which the body fails to maintain a blood sugar (glucose) level within the normal range. It is estimated that over 300 million people worldwide have diabetes, with this number accelerating rapidly. Diabetes often leads to many serious complications and thus is a leading cause of death. Therefore, a critical issue for those with diabetes is accurate glucose monitoring and treatment with the appropriate amounts of insulin or other drugs.

Blood glucose measurements have typically involved withdrawing a droplet of blood, followed by optical or electrochemical measurements. However, the drawbacks of this approach include pain, inconvenience, poor accuracy, etc. Implantable glucose sensors are also of interest, but these often suffer from lifetime (e.g., fouling) issues. Therefore, the focus of this special issue is on contributions that demonstrate new glucose sensing strategies, concepts, and designs, as well as improved understanding of sensor operation, with an emphasis on improved reliability, lifetime, continuous glucose monitoring, response time, accuracy, etc. Although the recent focus has been on the use of electrochemical methods, contributions involving spectroscopic methods or other novel and non-invasive sensing strategies are also welcome.

Dr. Viola Birss
Guest Editor

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Keywords

  • continuous glucose monitoring
  • implantable glucose sensors
  • glucose sensor nanostructures
  • sensor protection from biofouling
  • glucose sensor/insulin platforms
  • non-enzymatic sensors
  • calibration and assessment criteria

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Published Papers (1 paper)

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Review
Recent Advances in Fluorescent Arylboronic Acids for Glucose Sensing
by Jon Stefan Hansen and Jørn Bolstad Christensen
Biosensors 2013, 3(4), 400-418; https://doi.org/10.3390/bios3040400 - 10 Dec 2013
Cited by 28 | Viewed by 11341
Abstract
Continuous glucose monitoring (CGM) is crucial in order to avoid complications caused by change in blood glucose for patients suffering from diabetes mellitus. The long-term consequences of high blood glucose levels include damage to the heart, eyes, kidneys, nerves and other organs, among [...] Read more.
Continuous glucose monitoring (CGM) is crucial in order to avoid complications caused by change in blood glucose for patients suffering from diabetes mellitus. The long-term consequences of high blood glucose levels include damage to the heart, eyes, kidneys, nerves and other organs, among others, caused by malign glycation of vital protein structures. Fluorescent monitors based on arylboronic acids are promising candidates for optical CGM, since arylboronic acids are capable of forming arylboronate esters with 1,2-cis-diols or 1,3-diols fast and reversibly, even in aqueous solution. These properties enable arylboronic acid dyes to provide immediate information of glucose concentrations. Thus, the replacement of the commonly applied semi-invasive and non-invasive techniques relying on glucose binding proteins, such as concanavalin A, or enzymes, such as glucose oxidase, glucose dehydrogenase and hexokinases/glucokinases, might be possible. The recent progress in the development of fluorescent arylboronic acid dyes will be emphasized in this review. Full article
(This article belongs to the Special Issue Recent Advances in Glucose Sensors)
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