Stimuli-Responsive Multifunctional Biosensors for Diagnostic and Therapeutic Applications
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".
Deadline for manuscript submissions: 28 February 2027 | Viewed by 86
Editor
Interests: biomolecules; biomass; self-assembly; biomimetic synthesis; biomedicine; tissue engineering; biosensors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Biosensing technologies have advanced rapidly in recent years, yet conventional biosensor systems remain largely passive, providing static readouts without adapting to dynamic chemical, physical, and biological environments. The emergence of stimuli-responsive multifunctional biosensors represents a transformative shift toward intelligent platforms capable of integrating sensing, signal transduction, and therapeutic response within a single system. These biosensors are designed to detect specific biochemical or physical stimuli, such as pH, reactive oxygen species, enzymes, ions, or temperature, and convert them into measurable outputs while simultaneously enabling controlled actuation.
Recent progress in advanced materials, including stimuli-responsive hydrogels, functional nanozymes, nucleic acid/protein/peptide assemblies, and two-dimensional nanomaterials, has enabled the development of biosensors with enhanced sensitivity, lower detection limits, and multifunctionality. These biosensor systems show great promise in complex disease microenvironments, such as inflammation, infection, cancer, and neural injury, where real-time monitoring and function-regulated therapy are critically needed. By incorporating multi-stimuli responsiveness and high-performance sensing mechanisms, such biosensor platforms can improve diagnostic accuracy and enable precision interventions.
Therefore, this Special Issue aims to highlight recent advances in the design and applications of stimuli-responsive multifunctional biosensors for biomedical diagnostics and therapy, with a focus on innovative materials, integrated functionalities, and translational potential.
We invite you to submit original research articles, short communications, and reviews on stimuli-responsive multifunctional biosensors to this Special Issue.
Prof. Dr. Gang Wei
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- stimuli-responsive materials
- hydrogels
- nanozymes
- biomolecular assemblies
- pH-responsive biosensors
- ROS-responsive biosensors
- enzyme-responsive biosensors
- ions-responsive biosensors
- temperature-responsive biosensors
- diagnostics
- therapy
- biomedicine
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