DNA Damage Repair and Cancer Therapeutics
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biophysics: Structure, Dynamics, and Function".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 1868
Special Issue Editor
Special Issue Information
Dear Colleagues,
We would like to invite you to contribute to a Special Issue on "DNA Damage Repair and Cancer Therapeutics" in the journal Biomolecules. DNA damage and its repair mechanisms are critical areas of research as they play a fundamental role in maintaining genomic stability and preventing cancer. Defects in these processes, particularly in genes such as BRCA1 and BRCA2, can lead to the development and progression of cancers. Understanding the role of these mechanisms in cancer is essential for developing novel therapies that address the significant need for effective cancer treatments.
This Special Issue aims to bring together cutting-edge research and reviews that explore the intricate relationship between DNA repair mechanisms and cancer treatment strategies. By focusing on this critical intersection, we seek to highlight innovative therapeutic approaches and deepen our understanding of how targeting DNA repair pathways can enhance cancer treatment outcomes, which is of great interest to the field at large. In this Special Issue, original research articles and reviews are welcome.
Research areas may include (but are not limited to) the following:
- Mechanisms of DNA damage and repair;
- The role of DNA repair pathways in cancer development;
- Targeting DNA repair mechanisms in cancer therapy;
- PARP inhibitors and other DNA repair inhibitors;
- Combination therapies involving DNA repair inhibitors;
- Biomarkers for DNA repair defects in cancer;
- Personalized medicine approaches based on DNA repair profiles;
- Immunotherapy and DNA damage response.
We look forward to receiving your contributions. We believe that this Special Issue will significantly advance our understanding of DNA damage repair and its potential in cancer therapy. Please do not hesitate to reach out regarding your interest or any questions relating to this Special Issue. If you are unable to contribute, we would greatly appreciate you sharing the details of this Special Issue with peers who may be interested.
Dr. Wenjing Li
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- DNA damage repair
- cancer therapy
- genomic stability
- targeted therapy
- biomarkers
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