Special Issue "Plant Polyphenols in the Immune and Inflammatory Responses"

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Natural and Bio-inspired Molecules".

Deadline for manuscript submissions: 15 October 2022 | Viewed by 48

Special Issue Editor

Dr. Heping Cao
E-Mail Website
Guest Editor
Southern Regional Research Center, US Department of Agriculture, LA 70124, USA
Interests: biochemistry and molecular biology of human nutrition and natural products with a focus on plant polyphenols from green tea, cinnamon, and cottonseed; biochemical genetics and metabolic pathways- carbohydrate, lipid, and RNA metabolism; protein/enzyme expression, purification, structure, function, enzymology, and proteomics; signal transduction pathways- insulin, tristetraprolin, and brassinosteroid

Special Issue Information

Dear Colleagues,

Inflammation and associated immune diseases have placed a heavy burden on the health care system. Drug treatment for reducing inflammation and related diseases has not been satisfactory. Complementary and alternative approaches need to be evaluated.

Plant extracts have historically been used as alternative medicines for the prevention, alleviation, and cure of various diseases. The mechanisms of how bioactive plant extracts work are poorly understood, due, in part, to the lack of knowledge of the structures of bioactive components in most extracts.

Plant polyphenols are major bioactive compounds in plant extracts. They are produced from the plant flavonoid biosynthetic pathway and used naturally for plant defenses against predators. Plant polyphenols are present in most diets and are beneficial to human health. They regulate mammalian gene expression in numerous studies. The anti-inflammatory activities of plant polyphenols are proposed to play an important role in the mediation of various health conditions by these alternative therapies; however, these anti-inflammatory mechanisms are not completely understood.

This Special Issue aims to highlight plant polyphenols in the immune and inflammatory response. Topics include plant polyphenol extraction, identification, bioactivity, structure-function relationship, molecular mechanisms at DNA, RNA, protein, and metabolic levels. We welcome comprehensive reviews and original research papers.

Dr. Heping Cao
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • plant polyphenol
  • bioactivity
  • immunity
  • inflammation; molecular mechanism
  • structure-function relationship

Published Papers

This special issue is now open for submission.
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