The Role of Epigenetic Regulation in Cancer

Dear Colleagues,

Genes and environment jointly determine the phenotype of organisms, both in physiological and pathological conditions. In recent decades, the emerging research on the chemical modification of DNA, RNA, and protein provides new insights into the epigenetic roles in the occurrence and progress of inflammation and cancer.

This special issue of biomolecules will focus on the latest progress in the role of epigenetic regulation in inflammation and cancer. Taking the epigenetic studies of RNA as an example, the roles, functions, and biological processes of m6A, m5C, m1a, m7G, ac4C, 2'- O methylation, and other types of chemical modifications in inflammation (eg: Alzheimer's disease, heart disease, type 2 diabetes, rheumatoid arthritis, and ankylosing spondylitis) and cancer are all our research areas of concern. In particular, we welcome original studies that are sufficiently novel, such as the single cell cancer epigenetics, regulatory roles of lncRNA and small RNA in epigenetics, epigenomics and social epigenomics, the use of multi-omics or other novel technical means to explore epigenetic regulation in inflammation-related diseases and cancer. In depth reviews in this direction are also welcome.

Prof. Dr. Ye Wang
Dr. Anton Buzdin
Prof. Dr. Xinmin Li
Guest Editors

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