The Kynurenine Pathway in Mood Disorders: From Mechanisms to Therapeutics
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biological Factors".
Deadline for manuscript submissions: 17 November 2026 | Viewed by 827
Special Issue Editor
Special Issue Information
Dear Colleagues,
The association of the kynurenine (Kyn) pathway of tryptophan catabolism with depression was suggested about 55 years ago. Importantly, key enzymes of the Kyn pathway are regulated by major factors associated with mood disorders: stress and inflammation. Dysregulation of the Kyn pathway might contribute to metabolic syndrome, which is highly associated with mood disorders.
Studies of the Kyn pathway in mood disorders are growing exponentially. This Special Issue, The Kynurenine Pathway in Mood Disorders: From Mechanisms to Therapeutics, aims to attract the most recent data on Kyn pathway abnormalities in mood disorders, with an emphasis on their translational potential.
Prof. Dr. Gregory F. Oxenkrug
Guest Editor
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Keywords
- kynurenine
- tryptophan
- mood disorders
- stress
- inflammation
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