Special Issue "Hydrogen Sulfide-Based Therapeutics"

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Chemical Biology".

Deadline for manuscript submissions: 31 May 2020.

Special Issue Editors

Prof. Dr. Harry van Goor
E-Mail Website
Guest Editor
Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands
Interests: hydrogen sulfide; gasotransmitters; nitric oxide; redox status; kidney disease; aging
Special Issues and Collections in MDPI journals
Prof. Dr. Jaap A. Joles
E-Mail Website
Guest Editor
Department of Nephrology and Hypertension, Laboratory of Renal and Vascular Biology, University Medical Center Utrecht, POB 85500, 3508 GA Utrecht, The Netherlands
Interests: hydrogen sulfide; nitric oxide; hypertension; chronic kidney disease; cardiorenal syndrome; wearable/portable artificial kidney
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Hydrogen sulfide (H2S) is an endogenously produced gaseous signaling molecule that exerts various effects in mammals. It is the third gasotransmitter, in addition to NO and CO. Over the last decade, it has been shown that H2S has beneficial effects in the cardiovascular system, including vasodilation, antioxidant effects, and the suppression of inflammation. Various H2S donors have now been described, and some of these have progressed into clinical trials for a variety of indications, such as the inhibition of inflammation, calciphylaxis, and cardiovascular protection. Hydrogen sulphide research is rapidly progressing and is moving in a variety of directions. Biomolecules is devoting a Special Issue to highlight the importance of H2S in drug development and therapy.

The Issue on “Hydrogen Sulfide-Based Therapeutics” welcomes articles related to therapeutic approaches of H2S in various animal models, the pharmacological role  of H2S production in biological systems, (patho-)physiological signalling in human and experimental disease, interactions of hydrogen sulphide with reactive oxygen species in the regulation of biological functions in health and disease, drug development related to H2S, and H2S metabolites as biomarkers in health and disease.

Prof. Dr. Harry van Goor
Prof. Dr. Jaap A. Joles
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Hydrogen sulfide
  • Diabetes
  • Aging
  • Cardiovascular
  • Acute and chronic kidney disease
  • Therapeutics
  • Pharmacology

Published Papers

This special issue is now open for submission.
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