Molecular Advances in Mechanism and Regulation of Lifespan and Aging

Dear Colleagues,

Aging is an important unsolved problem in biology. It is also by far the most significant risk factor for many major human diseases, such as cancer, heart disease, and Alzheimer’s disease. As medical advances extend the average lifespan, the already large public health significance of these aging-related diseases will only continue to grow.

Many recent studies have uncovered genes, pathways, and interventions that can have dramatic effects on aging in laboratory models, most of which suggest that their underlying biology may be conserved in humans.

This Special Issue aims to highlight recent advances that have been made in this field that deepen our understanding of genes, pathways, and interventions that alter aging in any model system. It also aims to highlight findings that shed light on aging-related biology that has the potential for translation to a human clinical setting, whether in the context of specific aging-related human diseases or of aging itself. We are also interested in new models that enhance our ability to study aging, such as biomarkers.

We encourage researchers interested in these topics to present original research articles in these areas. In addition, review articles that cover the related research and provide concluding remarks and an outlook will also be considered for inclusion in this Special Issue.

Dr. Mark McCormick
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• aging
• lifespan
• healthspan