Advances in Genetic and Epigenetic Gene Therapy for Diabetic Wound Healing
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Genetics".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 390
Special Issue Editor
Special Issue Information
Dear Colleagues,
Diabetic ulcers (DUs), complicated by infection/ischemia/high levels of reactive oxygen species, often suffer from poor perfusion, delayed healing and wound recurrence. Gene therapy is emerging as a promising approach for treating DUs by targeting specific genes to promote healing. This involves using genes, proteins, or peptides to stimulate tissue regeneration, improve angiogenesis and reduce inflammation at the wound site. Recently it has been noted that in addition to changes in gene expression, epigenetic changes also play a role in impaired diabetic wound healing, and thus epigenetic gene therapy has emerged as a promising avenue for treating DUs. This collection will focus on potential genetic and epigenetic gene therapy, including genes, proteins, peptides, DNA methylation modifiers, histone modifiers, microRNAs and others to treat and manage DUs.
Dr. Kanhaiya Singh
Guest Editor
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Keywords
- chronic wounds
- DFU
- wound healing
- diet
- diabetes
- obesity
- nutrition
- genomics
- epigenetics
- DNA methylation
- histone modifications
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