Advances in Microbial CRISPR Editing
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 52
Special Issue Editors
Interests: synthetic biology; CRISPR editing; experimental evolution; population genetics; microbial, enzymatic, and metabolic engineering; yeast and bacterial functional genomics
Special Issue Information
Dear Colleagues,
CRISPR-Cas systems have revolutionized microbial genome editing, enabling precise and efficient genetic modifications in fungi, bacteria, and archaea. These technologies have expanded beyond model organisms, allowing applications in microbiome engineering, metabolic pathway optimization, and microbial synthetic biology. Advances in base and prime editing, multiplexed genome engineering, and CRISPR-driven biocontainment are reshaping microbial research and biotechnology. However, challenges remain in improving editing precision, controlling mobile genetic elements, and ensuring evolutionary stability. This Special Issue explores the latest breakthroughs, novel CRISPR systems, and applications that push the boundaries of microbial engineering, paving the way for transformative innovations in medicine, industry, and environmental sciences.
Dr. Dongdong Yang
Prof. Dr. Rongming Liu
Guest Editors
Manuscript Submission Information
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Keywords
- CRISPR-Cas
- microbial genome editing
- synthetic biology
- base and prime editing
- multiplexed CRISPR engineering
- microbiome manipulation
- phage and plasmid control
- evolutionary stability of CRISPR edits
- CRISPR-driven biocontainment
- novel CRISPR systems
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