Melatonin in Normal Physiology and Disease, 2nd Edition
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 773
Special Issue Editor
Interests: circadian rhythms; melatonin; immune system; adrenergic modulation of hematopoiesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Following a very successful first run, we are pleased to announce the launch of a second edition of this Special Issue on “Melatonin in Normal Physiology and Disease”.
In mammals, melatonin is synthesized in virtually all cells of the body, where it functions as an autocrine or paracrine messenger and as a cytoprotective agent by virtue of its detoxifying and antioxidant properties. However, it is the melatonin synthesized in the pineal gland that circulates in the blood in a circadian fashion, playing a vital role in the body. In fact, pineal melatonin transduces light as a basic environmental cue into an endocrine signal capable of synchronizing the entire organism during the photoperiod. As a result, virtually all physiological processes are affected and deranged pineal melatonin production is associated with various pathological states. Melatonin activates two high-affinity membrane receptors, the specific contribution of which to most of its effects is still not clear. This Special Issue aims to gather research articles or reviews on the role of melatonin in normal physiology, including emerging roles such as neurotrophic effects, human reproduction, and mesenchymal stem cell function. In addition, papers on the pathological significance of disturbed melatonin rhythms, as well as the related therapeutic possibilities in inflammatory disorders, skin diseases, viral and bacterial infections, neurodegenerative diseases, cancer, osteoporosis, and autoimmunity, are also welcome.
Dr. Georges Maestroni
Guest Editor
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Keywords
- circadian rhythms
- immunity
- skin
- reproduction
- aging
- viral and bacterial infection
- inflammation
- mesenchymal stem cells
- cancer
- neurodegenerative diseases
- osteoporosis
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Related Special Issue
- Melatonin in Normal Physiology and Disease in Biomolecules (6 articles)
