Cell-Material Interactions: From Biointerface to Cell Response
A special issue of Biology (ISSN 2079-7737).
Deadline for manuscript submissions: closed (15 November 2021) | Viewed by 8977
Special Issue Editor
Special Issue Information
The field of biomaterials has made remarkable advancements in the past few decades. The materials used have expanded from metals and synthetic polymers to a wide variety such as proteins, peptides, polysaccharides, and DNA. The applications of biomaterials has also broadened from a relatively narrow focus on prosthetic materials to find their use in cell and tissue scaffolds, artificial organs, drug delivery systems, antimicrobial agents, vaccine development, and the list is increasing. With these new applications, biomaterials are no longer desired to be biologically inert but designed to actively interact with tissue and cells to elicit an appropriate response. Therefore, better biomaterials design today necessitates a detailed understanding of their interaction with cells. In parallel, the introduction of exciting new tools and technology in cell and molecular biology, such as high-resolution microscopy, transcriptomic, and proteomic analysis enable understanding of cellular structure and function at an unprecedented detail.
This Special Issue aims to broadly encompass the question of how biomaterials work, focusing specifically on cellular interaction and response to biomaterials. The topics include but are not limited to: (1) Characterization of biomaterials interface with cells and tissues; (2) cell response to biomaterials-presented adhesion and diffusible signaling; (3) the effects of biophysical properties of materials (mechanical properties, topography, alignment, etc.) on cells; (4) targeting and delivery of drug carrier particles; (5) modulation of intracellular signaling by biomaterials; (6) cellular uptake and fate of biomaterials; (7) cell response to biomaterials such as viability, proliferation, development, and differentiation.
We invite original research articles and reviews for this Special Issue, covering the interdisciplinary research at the intersection of biomaterials science and cell biology. The Special Issue is expected to contribute to the advancement of knowledge and growth of interest in this exciting area.
Dr. Shantanu Sur
Guest Editor
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Keywords
- artificial extracellular matrix
- designer biomaterials
- cell-materials interface
- adhesion signaling
- mechanobiology
- intracellular signaling
- gene and protein expression
- tissue engineering
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