Special Issue "Mitophagy Pathways in Health and Disease"

A special issue of Biology (ISSN 2079-7737).

Deadline for manuscript submissions: 31 August 2020.

Special Issue Editors

Dr. G. Angus McQuibban
Guest Editor
Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1M1, Canada
Interests: mitophagy; parkinson disease; rhomboid protease
Dr. Thomas Hurd
Guest Editor
Department of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1M1, Canada
Interests: mitochondria; drosophila; germline

Special Issue Information

Dear Colleagues,

Mitochondria are critical regulators of cellular life and death through their metabolic and apoptotic pathways, respectively. Damage to mitochondrial lipids, proteins, and DNA is an occupational hazard as a consequence of energy production within the organelle. However, the cell has evolved elegant mechanisms to deal with this accumulation of damaged mitochondria, collectively termed mitophagy. Mitophagy is the selective removal of dysfunctional mitochondria via the autophagy pathway.

In this Special Issue entitled “Mitophagy Pathways in Health and Disease”, we invite the submission of original scientific reports, review articles, commentary and perspective pieces on the broad topic of mitophagy. We seek to cover the many and varied mitophagy pathways that have been characterized to date, including basic pathway dissection in model organisms and more translational studies involving human disease mechanisms. 

We trust this Special Issue will be a comprehensive collection of articles and an incredible resource for scientists both within the field of mitochondrial biology and for life science researchers in general.

Dr. G. Angus McQuibban
Dr. Thomas Hurd
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • mitophagy
  • neurodegeneration
  • models of human disease

Published Papers

This special issue is now open for submission.
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