BK Polyomavirus (BKPyV) Associated Nephropathy
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Infection Biology".
Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 3017
Special Issue Editor
Special Issue Information
Dear Colleagues,
BK polyomavirus (BKPyV) is a ubiquitous polyomavirus causing an asymptomatic primary infection that commonly occurs during childhood. BKPyV reactivation or infection is usually only observed in immunosuppressed individuals. Furthermore, BKPyV is the most important polyomavirus affecting renal transplant recipients and adequate management of this infection may have a great impact on allograft survival. BKPyV-associated nephropathy (BKVAN) is seen in about 5% of renal transplant patients and can lead to chronic allograft failure and even graft loss in up to 50% of cases in the pre-screening era. Additionally, BKVAN has also been described in stem cell transplanted patients recently, but unfortunately no causal therapy has been established yet. On the whole, further research in this severe disease is absolutely warranted, especially focused on screening strategies as well as therapy development. Interestingly, monitoring of specific immunity combined with viral load could be used to individually assess the risk of viral reactivation and the potential for virus control. However, cellular immunity and targeting the immune system also has the potential to be useful in drug development. Consequently, this Special Issue focusses on new aspects in BKVAN with an emphasis on cellular immunity and treatment development.
This Special Issue welcomes submissions of original research and review manuscripts focusing on BKVAN. The goal is to achieve a realistic overview of recent developments in this severe disease.
Prof. Dr. Oliver Hakenberg
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- BK polyomavirus (BKPyV)
- nephritis
- kidney transplantation
- stem cell transplantation
- immunosuppression
- cellular immunity
- cellular therapies
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
