AI-Enhanced Biomechanics and Rehabilitation Engineering

A Special Issue of Bioengineering (ISSN 2306-5354) belonging to the section "Biosignal Processing".

Deadline for manuscript submissions: closed (31 October 2025) | Viewed by 1912

Editors


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Guest Editor
Department of Biomedical, Industrial and Human Factors Engineering, Orthopaedic Surgery, Sports Medicine and Rehabilitation, Wright State University, 3640 Colonel Glenn Hwy, Dayton, OH 45435, USA
Interests: application of biomaterials; biomechanics; wear and fatigue related research in medical devices; mathematical modeling
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Guest Editor
Clinical Cardiac Electrophysiology, The Ohio State University Wexner Medical Center, Columbus, OK 43210, USA
Interests: biomaterials; clinical engineering; biomedical devices; cardiovascular engineering; biomedical instrumentation; biomechanical engineering; biomedical modeling; biomedical technology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
College of Engineering and Computer Science, Wright State University, Dayton, OH 45435, USA
Interests: advanced engineering materials; material property characterization and lifecycle assessment; biomechanics; biomedical engineering; bone biomechanics; mechanical testing; finite element modeling; biomedical devices
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

AI-enhanced biomechanics and rehabilitation Engineering involves the integration of artificial intelligence (AI) technologies into the field of biomechanics and rehabilitation engineering in order to enhance patient care and recovery. By utilizing AI algorithms and machine learning techniques, researchers and healthcare professionals are able to analyze large datasets of biomechanical and physiological information to develop personalized treatment plans and interventions for individuals with musculoskeletal injuries or disabilities.

This Special Issue will aim to explore innovative AI-driven solutions and their applications in the following areas:

  • Optimizing biomechanical modeling and analysis;
  • Enhancing the design and functionality of prosthetic devices;
  • Improving rehabilitation technologies and therapeutic strategies;
  • Personalizing rehabilitation protocols through predictive analytics and machine learning;
  • Addressing challenges and ethical considerations in AI applications for rehabilitation engineering;
  • AI predictive models for biomechanical behavior under different conditions, aiding in the simulation of complex biological systems and the prediction of injury risk.

Prof. Dr. Tarun Goswami
Dr. Anmar Salih
Dr. Farah Hamandi
Guest Editors

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Keywords

  • artificial intelligence
  • biomechanics
  • rehabilitation engineering
  • machine learning
  • predictive modeling
  • prosthetic
  • gait analysis, personalized healthcare
  • biomechanical data analysis
  • injury prevention
  • fatigue detection
  • custom orthopedic solutions
  • biomechanical simulation
  • biomechanical performance
  • AI in biomechanical research

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Published Papers (1 paper)

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Research

40 pages, 4349 KB  
Article
Kinetics and Fluid-Specific Behavior of Metal Ions After Hip Replacement
by Charles Thompson, Samikshya Neupane, Sheila Galbreath and Tarun Goswami
Bioengineering 2026, 13(1), 44; https://doi.org/10.3390/bioengineering13010044 - 30 Dec 2025
Viewed by 892
Abstract
Background: Total hip arthroplasty (THA) is a well-tolerated and effective procedure that can improve a patient’s mobility and quality of life. A main concern, however, is the release of metal ions into the body due to wear and corrosion. Commonly reported ions [...] Read more.
Background: Total hip arthroplasty (THA) is a well-tolerated and effective procedure that can improve a patient’s mobility and quality of life. A main concern, however, is the release of metal ions into the body due to wear and corrosion. Commonly reported ions are Co and Cr, while others, such as Ti, Mo, and Ni, are less frequently studied. The objective of this study was to characterize compartmentalization and time-dependent ion behaviors across serum, whole blood, and urine after hip prosthetic implantation. The goal of using Random Forest (RF) was to determine whether machine learning modeling could support temporal trends across data. Methods: Data was gathered from the literature of clinical studies, and we conducted a pooled analysis of the temporal kinetics from cohorts of patients who received hip prosthetics. Mean ion concentrations were normalized to µg/L across each fluid and weighted by cohort sample size. RF was used as a study-level test of predictive accuracy across ions. Results: For serum and whole blood, Co and Cr displayed one-phase association models, while Ti showed an exponential rise and decay. Ions typically rose quickly within the first 24 months postoperatively. Serum Co and whole blood had similar patterns, tapering off just under 2 µg/L, but serum Cr (~2.02 µg/L) was generally higher than that of whole blood (~0.99 µg/L). Mean urinary Co levels were greater than those of Cr, suggesting a larger, freely filterable fraction for Co. RF was implemented to determine predictive accuracy for each ion, showing a stronger fit for Co (R2 = 0.86, RMSE = 0.57) compared to Cr (R2 = 0.52, RMSE = 0.50). Conclusions: Sub-threshold exposure was prevalent across cohorts. Serum and whole blood Co and Cr displayed distinct kinetic profiles and, if validated, could support fluid-specific monitoring strategies. We present a methodology for interpreting ion kinetics and show potential for machine learning applications in postoperative monitoring. Full article
(This article belongs to the Special Issue AI-Enhanced Biomechanics and Rehabilitation Engineering)
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