Special Issue "Epigenetic and Transcriptional Regulation in Muscle Cells"

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editors

Dr. Iori Sakakibara
E-Mail Website
Guest Editor
Department of Nutritional Physiology, Institute of Medical Nutrition, Tokushima University Graduate School, Tokushima 7708503, Japan
Interests: skeletal muscle; epigenome; transcription
Special Issues and Collections in MDPI journals
Dr. Shinichiro Hayashi
E-Mail Website
Guest Editor
Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo 187-8502, Japan
Interests: skeletal muscle; satellite cell; transcription factor
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

We invite you to contribute to a Special Issue of the journal Applied Sciences, “Epigenetic and Transcriptional Regulation in Muscle Cells”, which aims to present recent advancements of epigenome analysis in the field of skeletal muscle.

Skeletal muscle is essential for the movement of organisms. Loss of muscle mass and function due to aging, cachexia or genetic diseases decreases health-related quality of life. Today, interest in muscle research is increasing with the growth of the elderly population; moving forward, it is important to study muscles from various points of view, such as development, metabolism, physiology, and pathology. The epigenome provides a basis of transcription via chemical modification of DNA and histones and acts as a cellular memory, regulating a wide range of organism activity. Several applications have already been developed for epigenetic analysis, such as ChIP-seq, ATAC-seq, mass spectrometry, and epigenome editing. These tools are also applicable to skeletal muscles with appropriate adaptation to skeletal muscle traits.

We thus invite you to submit your research on these topics in the form of original research papers, mini-reviews, and perspective articles.

Dr. Iori Sakakibara
Dr. Shinichiro Hayashi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Skeletal muscle
  • Myogenesis
  • Epigenome
  • DNA methylation
  • Histone acetylation
  • Histone methylation
  • Sarcopenia
  • Exercise
  • Cachexia
  • Transcription
  • Muscle atrophy
  • Muscle hypertrophy
  • Satellite cell

Published Papers

This special issue is now open for submission.
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