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Advanced Orthodontics and Dental Imaging Techniques

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Dentistry and Oral Sciences".

Deadline for manuscript submissions: 20 September 2026 | Viewed by 1046

Special Issue Editor


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Guest Editor
Center for Dental Medicine, Department of Orthodontics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetterstr. 55, 79106 Freiburg, Germany
Interests: MRI radiation-free visualization; 3D imaging; cone beam computer tomography (CBCT); digital imaging; clinical dentistry; diagnostic radiology; orthopedic surgery; orthognathic surgery; osseointegration; skeletal anchorage; digital orthodontics; lingual orthodontics

Special Issue Information

Dear Colleagues,

The field of orthodontics has seen remarkable developments in recent decades, leading to gentler treatments, shorter treatment times, and more functional and esthetic results. Central trends include individualized treatment concepts, computer-assisted planning, advanced bracket systems, and minimally invasive approaches.

In this Special Issue, we emphasize current research and advances in digital technologies and imaging, including AI-driven diagnostics, radiation-free MRI visualization of anatomical structures, and personalized orthodontic treatment strategies such as skeletal anchorage, lingual orthodontics, and orthognathic surgery. We also seek orthodontic accelerators, concepts in current research and implications from a cellular and molecular perspective that facilitate and speed up clinical translation.

Research articles, review articles and short communications are invited and welcome.

Prof. Dr. Britta A. Jung
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • digital technologies and imaging
  • MRI radiation-free visualization
  • skeletal anchorage
  • focal adhesion kinase
  • in vitro cell system(s)
  • mechanobiology
  • mechanotransduction
  • senescence
  • tissue homeostasis
  • wound healing
  • yes-associated protein
  • personalized treatment strategies
  • orthodontic accelerators

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Published Papers (2 papers)

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Research

24 pages, 6412 KB  
Article
SEM-Based Surface Imaging, Microhardness, and Cytocompatibility of Orthodontic Bite Ramp Materials: Clinical Implications for Wear Behavior and Occlusal Performance
by Roberta Condò, Maria Elena Cataldi, Loredana Cerroni, Gianluca Mampieri, Luca Imperatori, Julietta V. Rau and Marco Fosca
Appl. Sci. 2026, 16(11), 5236; https://doi.org/10.3390/app16115236 - 23 May 2026
Viewed by 241
Abstract
Surface hardness is a fundamental parameter influencing wear resistance, durability, and the interaction of occlusal ramps with opposing enamel during orthodontic treatment. Five commercially available materials (Harmonize, Leone F3172-01, Transbond™ XT, Band and Build LC, and Ultra Band-Lok) and one experimental material (Composite [...] Read more.
Surface hardness is a fundamental parameter influencing wear resistance, durability, and the interaction of occlusal ramps with opposing enamel during orthodontic treatment. Five commercially available materials (Harmonize, Leone F3172-01, Transbond™ XT, Band and Build LC, and Ultra Band-Lok) and one experimental material (Composite RK-F10) were evaluated for bite ramps. Twelve standardized specimens (n = 2 per material) were prepared using EVA molds and polymerized according to manufacturers’ instructions or internal protocols. Vickers microhardness (HV) was measured following ASTM E384-16 using a 500 g load, 20 s dwell time, and ten indentations per specimen. Load dependence was assessed (25–2000 g). Surface morphology was analyzed by SEM, and cytotoxicity of eluates was evaluated on dental pulp stem cells (DPSCs) and monocyte/macrophage cell lines using CCK-8 assays (ISO 7405, ISO 10993). Significant differences in hardness were observed among materials (p < 0.05). Harmonize (64.5 ± 1.6 HV), Band and Build LC (64.4 ± 1.9 HV), and Ultra Band-Lok (64.1 ± 2.0 HV) showed the highest values, whereas Transbond™ XT exhibited the lowest value (53.7 ± 6.0 HV). Composite RK-F10 demonstrated intermediate hardness and good cytocompatibility. SEM analysis revealed differences in surface homogeneity and filler distribution. Overall, the materials exhibited distinct mechanical and biological profiles. The combined Vickers microhardness, short-term (24 h) cytotoxicity, and SEM data provide an integrated preliminary in vitro characterization of materials for bite ramps. The observed differences contribute to a comparative description of their physico-biological behavior. Full article
(This article belongs to the Special Issue Advanced Orthodontics and Dental Imaging Techniques)
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18 pages, 4215 KB  
Article
3D Dental Model Measurement System with Measurement Templates: Toward Variable Application
by Koga Harumichi, Taki Katsuhiko, Ogawa Nobuhiro, Masugi Ayano, Umehara Akito and Haga Shugo
Appl. Sci. 2026, 16(9), 4267; https://doi.org/10.3390/app16094267 - 27 Apr 2026
Viewed by 534
Abstract
Accurate, standardized dental model measurements remain labor-intensive and difficult to scale in orthodontics. This technical development study aimed to develop and preliminarily evaluate a semiautomated three-dimensional (3D) dental cast measurement system using standardized measurement templates (patent pending). The workflow integrates robotic handling of [...] Read more.
Accurate, standardized dental model measurements remain labor-intensive and difficult to scale in orthodontics. This technical development study aimed to develop and preliminarily evaluate a semiautomated three-dimensional (3D) dental cast measurement system using standardized measurement templates (patent pending). The workflow integrates robotic handling of models, X-ray CT acquisition of volumetric data, optional intraoral-scan polygonal data (e.g., STL), template generation from 3D data, and orthodontist-guided landmark placement, after which dedicated software retrieves 3D coordinates and performs automated measurements and visualization. The system was demonstrated on four standard models scanned by X-ray CT. It produced automated aggregation of measurements and 3D visual outputs, and enabled calculation of conventional indices as well as template-based metrics such as palatal volume and cusp height variation. This semiautomated approach combines mechanical efficiency with expert oversight, providing a standardized alternative to manual measurement and a foundation for broader applications in orthodontic, prosthodontic, and forensic contexts. Full article
(This article belongs to the Special Issue Advanced Orthodontics and Dental Imaging Techniques)
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