Oxidative Stress as a Therapeutic Target of Alzheimer’s Disease—2nd Edition

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 31 May 2026

Special Issue Editors


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Guest Editor
Department of Pharmacy—Pharmaceutical Sciences, University of Bari Aldo Moro, Bari, Italy
Interests: cell culture; transfection; cancer biology; pharmaceutical biotechnology; medicinal chemistry

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Guest Editor
Dipartimento di Farmacia—Scienze del Farmaco, Università degli Studi di Bari, Bari, Italy
Interests: medicinal chemistry; serotonin receptors; dopamine receptors; formyl peptide receptors; positron emission tomography; fluorescent ligands
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Special Issue Information

Dear Colleagues,

Following the success of the first edition of our Special Issue, which resulted in the compilation of interesting and inspiring research and review papers, we are happy to announce its second edition, entitled “Oxidative Stress as a Therapeutic Target of Alzheimer’s Disease—2nd Edition”.

Once again, we will focus on the current advances regarding antioxidant research for the development of new drugs targeting the onset and progression of Alzheimer's Disease (AD). While the oxidative stress phenomena that accompany neuroinflammation are strongly linked to the neurodegeneration that leads to cognitive symptoms, antioxidant therapy is still controversial and lacks any clinical substantiation.

This field of research is, however, still highly dynamic and diverse, comprising different strategies such as the employment of scavenger compounds and enzyme inhibition. The goal of this Special Issue is to gather the latest research regarding the physiopathology of oxidative stress in AD and the development of new therapeutic agents targeting this phenomenon. All approaches to this are welcome.

We eagerly look forward to your contributions.

Dr. Leonardo Brunetti
Prof. Marcello Leopoldo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Alzheimer's disease
  • oxidative stress
  • therapeutic target
  • antioxidant
  • neurodegeneration

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