Oxidative Stress and Inflammation in Cancer Biology—2nd Edition
A Special Issue of Antioxidants (ISSN 2076-3921) belonging to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 28 February 2027 | Viewed by 1
Editors
2. Instituto de Investigación Sanitaria de las Islas Baleares (IdISBa), Hospital Universitario Son Espases, Edificio S, Palma, Illes Balears, Spain
3. CIBER Fisiopatología Obesidad y Nutrición, Instituto Salud Carlos III, Madrid, Spain
Interests: cancer biology; oxidative stress; mitochondria; inflammation; cancer biomarkers; molecular biology; breast cancer; colorectal cancer
Special Issues, Collections and Topics in MDPI journals
2. Instituto de Investigación Sanitaria de las Islas Baleares (IdISBa), Hospital Universitario Son Espases, Edificio S, Palma, Illes Balears, Spain
Interests: oncology; breast cancer; oxidative stress; mitochondria; senescence; antibody–drug conjugates; drug resistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative stress and inflammation are tightly interconnected processes that play a central role in cancer initiation, progression, and therapeutic response. The imbalance between reactive oxygen species (ROS) production and antioxidant defenses leads to molecular damage and genomic instability, while chronic inflammation contributes to a tumor-promoting microenvironment that supports cancer cell survival, proliferation, and metastasis.
The first edition of this Special Issue highlighted the importance of these processes in cancer biology, bringing together contributions that explored key molecular mechanisms, signaling pathways, and potential therapeutic strategies. Since then, significant advances have been made in understanding the dynamic interplay between oxidative stress, inflammation, and tumor–microenvironment interactions, particularly in the context of metabolic reprogramming, mitochondrial dysfunction, and biomarker discovery.
This second edition aims to further expand on these advances by welcoming original research and review articles that address emerging concepts and translational approaches. Topics of interest include redox signaling, inflammation-driven tumor progression, novel antioxidant strategies, and the identification of clinically relevant biomarkers.
By integrating basic, translational, and clinical perspectives, this Special Issue seeks to provide updated insights into cancer biology and to support the development of more effective and personalized therapeutic strategies.
Dr. Jorge Sastre-Serra
Dr. Mercedes Nadal-Serrano
Guest Editors
Manuscript Submission Information
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Keywords
- oxidative stress
- inflammation
- signaling pathways
- tumor microenvironment
- biomarkers
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Related Special Issue
- Oxidative Stress and Inflammation in Cancer Biology in Antioxidants (6 articles)

