Antioxidant Defenses Against Stress Caused by Physical or Chemical Environmental Changes

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 30 July 2025 | Viewed by 537

Special Issue Editor


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Guest Editor
Department of Biology, University of Padova, Padua, Italy
Interests: physiological responses of animals to environmental conditions where there are chemical contaminants that can also induce oxidative stress
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Special Issue Information

Dear Colleagues,

In this Special Issue, entitled “Antioxidant Defenses Against Stress Caused by Physical or Chemical Environmental Changes”, we aim to consider the different antioxidant responses that organisms of all kingdoms put in place following exposure to stressors of both a physical and chemical nature. For example, heat stress is one of the most severe hurdles impacting growth, immunity, homeostasis, and productivity.

The phototoxicity of several environmental contaminants by UV light has been reported in many studies.

Elevated CO2 and O3, singly and in combination, have effects on various physiological and biochemical parameters.

Among the xenobiotics that can cause oxidative stress, heavy metals and benzopyrene are common.

Many classes of compounds, including organophosphorus pesticides, are able to cause oxidative stress that affects the regulation of the delicate cellular redox balance, for example, tissue modeling.

Oxidative stress is, therefore, overcome by antioxidant defenses.

Therefore, in this Special Issue, we aim to collate the most recent studies regarding the different environmental factors that can disturb the normal physiological redox state, considering both the effects and response mechanisms.

Dr. Paola Irato
Guest Editor

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Keywords

  • antioxidant defenses
  • oxidative stress
  • redox state
  • physical stress
  • chemical stress
  • environmental changes
  • kingdoms living
  • heat stress
  • UV light
  • CO2 and O3
  • heavy metals

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Published Papers (1 paper)

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Research

14 pages, 1346 KiB  
Article
Effects of Mogroside V on Quality and Antioxidant Activity of Boar Frozen–Thawed Sperm
by Heming Sui, Xin Wang, Kunlong Hu, Xiaoyu Zuo, Haonan Li, Zhengyu Diao, Jiajing Feng, Yunhai Zhang and Zubing Cao
Antioxidants 2025, 14(6), 622; https://doi.org/10.3390/antiox14060622 - 23 May 2025
Viewed by 346
Abstract
Cryopreserved pig semen tends to produce excessive reactive oxygen species (ROS) during the thawing process, which leads to a decline in semen quality during in vitro storage. Mogroside V (MV) has been proven to be an effective antioxidant, and previous research has shown [...] Read more.
Cryopreserved pig semen tends to produce excessive reactive oxygen species (ROS) during the thawing process, which leads to a decline in semen quality during in vitro storage. Mogroside V (MV) has been proven to be an effective antioxidant, and previous research has shown that MV can delay oocyte aging and improve the in vitro maturation efficiency of pig oocytes. However, the role of MV in the cryopreservation capacity of animal sperm remains unclear. To evaluate the effect of MV on sperm motility after thawing, different concentrations of MV (0, 25, 50, 75, 100 μmol/L) were added to the thawing medium. By comparing the sperm motility and kinematic parameters in the thawing medium with different MV concentrations and incubation times (0, 1, 2, and 4 h), we ultimately selected sperm thawed immediately in the medium supplemented with 75 μmol/L MV for subsequent experiments. Compared with the control group, the sperm thawing medium containing MV improved sperm quality during the freeze–thaw process. Immediate evaluation after thawing at 37 °C showed that supplementation with 75 μmol/L MV produced an optimal effect on the maintenance of motility, plasma membrane integrity, the acrosome integrity, the ROS levels, and the T-AOC activity. In conclusion, MV supplementation improves the quality of frozen–thawed sperm by enhancing sperm function and preventing oxidative stress. Full article
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