Phenolic Antioxidants—2nd Edition

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Extraction and Industrial Applications of Antioxidants".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 779

Special Issue Editors


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Guest Editor
Department of Biochemistry, Memorial University of Newfoundland, St. John’s, NL A1C 5S7, Canada
Interests: antioxidants; radical scavenging; phenolic and polyphenolic compounds; oxidation control; disease risk reduction; bioactivity; health benefits; action mechanisms
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Special Issue Information

Dear Colleagues,

In view of the great response we received to the previous Special Issue “Phenolic Antioxidants”, we have decided to revisit this topic.

Phenolic compounds include tocopherols and tocotrienols, collectively known as tocols, with vitamin E activity, as well as secondary plant metabolites (i.e., phenolic acids, flavonoids, stilbenes, coumarins, lignans, and tannins). Phenolic compounds protect plants and plant foods from biotic and abiotic oxidative stress as well as herbivory. This property remains important therefore until the post-harvest time. From the food processing standpoint, lipid oxidation is the most important deterioration problem faced by the food industry. The consequences of lipid oxidation are noted mainly by the negative changes found in terms of nutritional quality, food safety, and the sensory characteristics of food. Therefore, natural antioxidants are also crucial ingredients employed by the food industry to decrease and/or prevent lipid oxidation. However, phenolic compounds are not only good for plant health, but also engender a myriad of other bioactivities. The health benefits of phenolic compounds, in vitro and in vivo, are supported by epidemiological, animal, and human studies. Phenolics may act as free radical terminators, metal chelators, but their antioxidant properties are also important to overcoming inflammatory responses caused by different factors including exposure to xenobiotics and pathogenic microorganisms.

This Special Issue invites contributions addressing the antioxidant properties of phenolic compounds in plants, plant foods, and the by-products thereof as well as their metabolites and derivatives. Original articles or review papers focusing on phenolic antioxidants and their impact on agronomical/plant science, food science, nutrition and health will be considered.

Dr. Adriano Costa de Camargo
Prof. Dr. Fereidoon Shahidi
Guest Editors

Manuscript Submission Information

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Keywords

  • phenolics
  • phenolic compounds
  • antioxidants

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Published Papers (1 paper)

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Research

25 pages, 2230 KiB  
Article
Combining Abiotic Stresses as a Low-Cost Strategy for Increasing the Phenolic Content in Apple Agro-Industrial By-Products
by Esteban Villamil-Galindo, Daniel A. Jacobo-Velázquez and Andrea Marcela Piagentini
Antioxidants 2025, 14(3), 287; https://doi.org/10.3390/antiox14030287 - 27 Feb 2025
Viewed by 556
Abstract
The circular economy approach offers innovative solutions for valorizing apple by-products through biofortification strategies transforming waste into high-value products and reducing environmental impact. This study evaluates innovative solutions for valorizing Granny Smith apple peel (RM) through biofortification in phenolic compounds using individual or [...] Read more.
The circular economy approach offers innovative solutions for valorizing apple by-products through biofortification strategies transforming waste into high-value products and reducing environmental impact. This study evaluates innovative solutions for valorizing Granny Smith apple peel (RM) through biofortification in phenolic compounds using individual or combined abiotic stresses, like wounding stress and ultraviolet A (UVA) radiation. The effects of cutting type (Ct) [whole (C1), 5 mm (C2), 1.5 mm (C3)], storage temperature (ST) [20, 15, 10, 5 °C], and storage time (TM) [0, 12, 24, 48, 72 h] on phenylalanine ammonia-lyase (PAL) and polyphenol oxidase (PPO) activity, total phenolic content (TPC), and phenolic profiles were studied first. The results show that higher stress intensity (C3, 15 °C, 48 h) significantly enhanced secondary metabolism, leading to notable increases in PAL activity (1201%), PPO activity (308%), TPC levels (108–118%), and Procyanidin B2 (PACB2, 22%), the predominant phenolic compound. These changes were critical for improving the bioactive properties and antioxidant potential of RM. The second assay combined wounding stress (same levels of Ct and ST of previous assay, TM: 56 h) with UVA radiation (UVA-D) [0, 86.4 KJ m−2, 172.8 KJ m−2], determining the optimal conditions (C3, UVA-D 66 KJ m−2, 17 °C) for maximizing PAL activity (0.12–0.20 ΔA h⁻1 mg⁻1), and TPC (3.3 g GAE kg⁻1). This study demonstrates the potential of combined abiotic stresses as cost-effective scalable tools to biofortify RM, promoting the sustainable and value-added utilization of agro-industrial by-products. Full article
(This article belongs to the Special Issue Phenolic Antioxidants—2nd Edition)
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