Advances in Oxidative Stress, Mitochondrial Dysfunction and Antioxidant Therapies in Endocrine and Metabolic Disorders
A Special Issue of Antioxidants (ISSN 2076-3921) belonging to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 28 February 2027 | Viewed by 560
Editors
Interests: bariatric surgery; obesity; gut microbiota; micronutrient deficiency; probiotics
Special Issues, Collections and Topics in MDPI journals
Interests: diabetes; PCOS; antioxidant; inflammation; phytochemical; oxidative stress; NLRP3 inflammasome
Special Issue Information
Dear Colleagues,
Oxidative stress and mitochondrial dysfunction are increasingly being recognized as key contributors to the pathogenesis and progression of endocrine and metabolic disorders. Excessive production of reactive oxygen species (ROS), impaired antioxidant defense mechanisms, and alterations in mitochondrial bioenergetics have been implicated in a wide range of conditions, including diabetes mellitus, obesity, metabolic syndrome, thyroid diseases, adrenal disorders, osteoporosis, and reproductive endocrinopathies. These processes contribute to chronic inflammation, insulin resistance, cellular dysfunction, and tissue damage, ultimately affecting disease onset, progression, and clinical outcomes.
Recent advances in molecular biology, metabolomics, and redox medicine have improved our understanding of the complex interactions between oxidative stress, mitochondrial homeostasis, and endocrine regulation. Moreover, growing evidence has highlighted the therapeutic potential of antioxidants, mitochondrial-targeted interventions, and lifestyle-based strategies in preventing or mitigating disease-related complications.
This Special Issue aims to provide a comprehensive overview of current research on the role of oxidative stress and mitochondrial dysfunction in endocrine and metabolic diseases. We welcome the submission of original research articles, reviews, systematic reviews, and meta-analyses that address molecular mechanisms, biomarkers, novel antioxidant therapies, mitochondrial-targeted treatments, redox signaling pathways, and translational approaches with potential clinical applications. By bringing together multidisciplinary perspectives, this Special Issue seeks to advance knowledge and foster innovative therapeutic strategies in endocrine and metabolic medicine.
Prof. Dr. Adriana Florinela Càtoi
Guest Editor
Dr. Lia Oxana Usatiuc
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- reactive oxygen species (ROS)
- mitochondrial bioenergetics
- insulin resistance
- antioxidant therapy
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