Multifunctional Nanoparticles and Nano-Enabled Pesticides, Herbicides and Fertilizers in Agricultural Applications

A special issue of Agronomy (ISSN 2073-4395). This special issue belongs to the section "Agroecology Innovation: Achieving System Resilience".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 8212

Special Issue Editors


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Guest Editor
Graduate and Research Division, Engineering Faculty, Universidad Autónoma de Querétaro, Cerro de las Campanas, Santiago de Querétaro 76010, Mexico
Interests: nanotoxicology; characteristics of the chemical components of particulate matter; source apportionment of particulate matter; analytical methods for emerging contaminants
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Guest Editor
Faculty of Engineering, Autonomous University of Querétaro, Campus Amazcala, Carretera Chichimequillas, El Marqués, Querétaro 76265, Mexico
Interests: secondary metabolites; nutraceuticals; biotic and abiotic stress
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Special Issue Information

Dear Colleagues,

Nanotechnology has revolutionized agricultural sciences, offering innovative solutions to enhance crop productivity, mitigate environmental stress, and reduce chemical inputs. Among these advancements, multifunctional nanoparticles and nano-enabled agrochemicals (pesticides, herbicides, and fertilizers) have emerged as promising tools to increase agricultural sustainability while ensuring food security. These nanomaterials enable the targeted delivery, controlled release, and enhanced bioavailability of active compounds, minimizing unintended environmental impacts. However, challenges related to nanotoxicity, regulatory frameworks, and large-scale implementation still require further investigation. This Special Issue aims to explore recent breakthroughs and future perspectives in the development and application of nanotechnology in agriculture, with a particular focus on nano-enabled agrochemicals and their role in sustainable farming.

The development of nano-enabled pesticides, herbicides, and fertilizers presents an opportunity to overcome these challenges by enhancing efficiency, reducing dosage requirements, and ensuring precise delivery mechanisms. Additionally, the multifunctionality of nanoparticles—such as their antimicrobial properties, controlled release capabilities, and plant stress mitigation potential—positions them as cutting-edge tools in modern agricultural practices.

This Special Issue will provide a comprehensive platform for the latest advances in multifunctional nanoparticles and nano-enabled agrochemicals in agricultural applications. It aims to highlight the following topics:

  • Novel nanomaterials designed for precision agriculture.
  • Advanced formulations of nano-pesticides, nano-herbicides, and nano-fertilizers.
  • Mechanisms of interaction between nanoparticles and plant systems.
  • Environmental and toxicological considerations of nano-agrochemicals.
  • The role of nanotechnology in enhancing crop resilience to biotic and abiotic stress.
  • Regulatory frameworks and sustainability considerations in nano-agriculture.

We invite high-quality original research articles, reviews, and perspectives addressing, but not limited to, the following topics:

  • The synthesis and characterization of nano-enabled agrochemicals.
  • Experimental studies on the efficacy, uptake, and translocation of nano-agrochemicals in crops.
  • Risk assessments on the environmental fate of nanomaterials in agricultural ecosystems.
  • Case studies on field applications of multifunctional nanoparticles.
  • Interdisciplinary approaches integrating nanotechnology with sustainable agriculture.

Policy and regulatory challenges surrounding nanotechnology applications in agriculture. 

Dr. Karen Esquivel Escalante
Prof. Dr. Ana Angelica Feregrino Perez
Guest Editors

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Agronomy is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanotechnology
  • nano-herbicides
  • nano-pesticides
  • nano-fertilizers
  • agriculture
  • food safety
  • plant stress
  • nanotoxicology
  • nutraceuticals
  • crop health

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Published Papers (3 papers)

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Research

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16 pages, 5926 KB  
Article
Green Synthesis of Silver Nanoparticles Using Aqueous Extract of Brucea javanica Residue: Enhanced Herbicidal Activity Against Paddy Weeds and Alleviated Phytotoxicity to Rice
by Fangxiang He, Jinhua Chen, Yanhui Wang and Liangwei Du
Agronomy 2026, 16(5), 506; https://doi.org/10.3390/agronomy16050506 - 25 Feb 2026
Viewed by 397
Abstract
The negative impacts caused by synthetic herbicides have necessitated research on environment-friendly and sustainable alternatives. In this study, a novel botanical nanoherbicide was developed through green synthesis of silver nanoparticles (Ag NPs) assisted by aqueous extract of Brucea javanica (BJ) residue. The BJ-Ag [...] Read more.
The negative impacts caused by synthetic herbicides have necessitated research on environment-friendly and sustainable alternatives. In this study, a novel botanical nanoherbicide was developed through green synthesis of silver nanoparticles (Ag NPs) assisted by aqueous extract of Brucea javanica (BJ) residue. The BJ-Ag NPs were characterized using ultraviolet–visible (UV–Vis) absorption spectroscopy, dynamic light scattering (DLS), zeta potential analysis, X-ray diffraction (XRD), and transmission electron microscopy (TEM) attached with energy dispersive X-ray spectroscopy (EDX). TEM images indicated that the BJ-Ag NPs were spherical with an average particle size of 12.75 nm. Meanwhile, the herbicidal activity against two paddy weeds (Echinochloa crusgalli and Bidens pilosa L.) and phytotoxicity to rice (Oryza sativa L.) were evaluated using the Petri dish method. Compared to the BJ residue extract, the BJ-Ag NPs exhibited enhanced inhibitory activity on the seed germination and seedling growth of two target weeds, while showing alleviated phytotoxicity and partially restored seedling vigor in rice. Obviously, positive impacts on both the weed and crop were obtained after synthesizing Ag NPs using the BJ residue extract. The results in this study demonstrated the potential of the BJ-Ag NPs as a sustainable, crop-friendly nanoherbicide for weed management in paddy fields. Full article
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Review

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21 pages, 1766 KB  
Review
Nanoparticles as Potential Eustressors in Plants
by Susana Rodríguez-Jurado, Ramón Gerardo Guevara-González, Humberto Aguirre-Becerra, Karen Esquivel-Escalante and Ana Angélica Feregrino-Pérez
Agronomy 2025, 15(9), 2186; https://doi.org/10.3390/agronomy15092186 - 13 Sep 2025
Cited by 3 | Viewed by 2590
Abstract
In recent years, the acceleration of climate change and the growing demand for higher-quality food to meet the needs of an expanding population have become pressing challenges. Nanotechnology has emerged as a promising tool in agriculture, particularly through the application of nanoparticles (NPs). [...] Read more.
In recent years, the acceleration of climate change and the growing demand for higher-quality food to meet the needs of an expanding population have become pressing challenges. Nanotechnology has emerged as a promising tool in agriculture, particularly through the application of nanoparticles (NPs). Recent studies highlight their potential to enhance plant performance, improve resistance to environmental stresses, and act as eustressors—stimuli that activate beneficial adaptive responses. Nanoparticles have been shown to stimulate plant defense systems (elicitation), promote growth and productivity, and improve crop quality by modulating physiological and biochemical pathways. Their role in enhancing adaptive capacity under diverse stress conditions makes them valuable candidates for sustainable agricultural strategies. However, a critical knowledge gap remains: the definition of eustress dose intervals. Establishing these thresholds is essential for maximizing the positive effects of NPs while minimizing risks. Finally, the need to define safe eustress dose intervals is highlighted as a critical step toward maximizing agricultural benefits while minimizing ecological and health risks. Full article
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57 pages, 1848 KB  
Review
Selenium Nanoparticles (Se NPs) as Agents for Agriculture Crops with Multiple Activity: A Review
by Dmitry E. Burmistrov, Sergey A. Shumeyko, Natalia A. Semenova, Alexey S. Dorokhov and Sergey V. Gudkov
Agronomy 2025, 15(7), 1591; https://doi.org/10.3390/agronomy15071591 - 29 Jun 2025
Cited by 16 | Viewed by 4239
Abstract
This review article is devoted to the use of selenium nanoparticles (Se NPs) in plant production. The review analyzes relevant literature data for the last 10 years, considering the effect of Se NPs application on morphometric and biochemical parameters of plants. A number [...] Read more.
This review article is devoted to the use of selenium nanoparticles (Se NPs) in plant production. The review analyzes relevant literature data for the last 10 years, considering the effect of Se NPs application on morphometric and biochemical parameters of plants. A number of actual works demonstrating the efficiency of Se NPs use in the composition of nanocomposites based on synthetic and natural polymers are considered separately. Possible mechanisms of Se NPs absorption and transport and their further activity in plant cells of agricultural crops in the context of biostimulating, biofortification, nutraceutical, and antioxidant activities of Se NPs, as well as the efficiency of Se NPs application under stress factors are discussed. The review provides data demonstrating the antibacterial and antifungal activities of Se NPs in the context of their activity against a wide range of phytopathogens. Also, we conduct a detailed comparative analysis of the relative efficiency of Se NP application with mineral Se-containing compounds (SeO32− and SeO42−), as well as organic forms of Se (SeCys and SeMet). Full article
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