Cells | Top Cited Papers in 2022 in the Section “Cellular Pathology”

“Detection of Hypoxia in Cancer Models: Significance, Challenges, and Advances”
by Inês Godet, Steven Doctorman, Fan Wu and Daniele M. Gilkes
Cells 2022, 11(4), 686; https://doi.org/10.3390/cells11040686
Available online: http://www.mdpi.com/2073-4409/11/4/686

“Molecular Mechanism of Lipotoxicity as an Interesting Aspect in the Development of Pathological States—Current View of Knowledge”
by Katarzyna Lipke, Adriana Kubis-Kubiak and Agnieszka Piwowar
Cells 2022, 11(5), 844; https://doi.org/10.3390/cells11050844
Available online: http://www.mdpi.com/2073-4409/11/5/844

“Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma”
by Jaafar Khaled, Maria Kopsida, Hans Lennernäs and Femke Heindryckx
Cells 2022, 11(4), 632; https://doi.org/10.3390/cells11040632
Available online: http://www.mdpi.com/2073-4409/11/4/632

“The Role of IL-6 in Cancer Cell Invasiveness and Metastasis—Overview and Therapeutic Opportunities”
by Magdalena Rašková, Lukáš Lacina, Zdeněk Kejík, Anna Venhauerová, Markéta Skaličková, Michal Kolář, Milan Jakubek, Daniel Rosel, Karel Smetan Jr. and Jan Brábek
Cells 2022, 11(22), 3698; https://doi.org/10.3390/cells11223698
Available online: http://www.mdpi.com/2073-4409/11/22/3698

“Myosteatosis in Cirrhosis: A Review of Diagnosis, Pathophysiological Mechanisms and Potential Interventions”
by Maryam Ebadi, Cynthia Tsien, Rahima A. Bhanj, Abha R. Dunichand-Hoedl, Elora Rider, Maryam Motamedrad, Vera C. Mazurak, Vickie Baracos and Aldo J. Montano-Loza
Cells 2022, 11(7), 1216; https://doi.org/10.3390/cells11071216
Available online: http://www.mdpi.com/2073-4409/11/7/1216

“Therapeutic Targeting of Intestinal Fibrosis in Crohn’s Disease”
by Giovanni Santacroce, Marco Vincenzo Lenti and Antonio Di Sabatino
Cells 2022, 11(3), 429; https://doi.org/10.3390/cells11030429
Available online: http://www.mdpi.com/2073-4409/11/3/429

“Epithelial Mesenchymal Transition (EMT) and Associated Invasive Adhesions in Solid and Haematological Tumours”
by David Greaves and Yolanda Calle
Cells 2022, 11(4), 649; https://doi.org/10.3390/cells11040649
Available online: http://www.mdpi.com/2073-4409/11/4/649

“Emerging Roles of Airway Epithelial Cells in Idiopathic Pulmonary Fibrosis”
by Ashesh Chakraborty, Michal Mastalerz, Meshal Ansari, Herbert B. Schiller and Claudia A. Staab-Weijnitz
Cells 2022, 11(6), 1050; https://doi.org/10.3390/cells11061050
Available online: http://www.mdpi.com/2073-4409/11/6/1050

“Targeting Histone Deacetylases in Idiopathic Pulmonary Fibrosis: A Future Therapeutic Option”
by Martina Korfei, Poornima Mahavadi and Andreas Guenther
Cells 2022, 11(10), 1626; https://doi.org/10.3390/cells11101626
Available online: http://www.mdpi.com/2073-4409/11/10/1626

“Açaì (Euterpe oleracea) Extract Protects Human Erythrocytes from Age-Related Oxidative Stress”
by Alessia Remigante, Sara Spinelli, Elisabetta Straface, Lucrezia Gambardella, Daniele Caruso, Giuseppe Falliti, Silvia Dossena, Angela Marino and Rossana Morabito
Cells 2022, 11(15), 2391; https://doi.org/10.3390/cells11152391
Available online: http://www.mdpi.com/2073-4409/11/15/2391

“Sarcopenia Is a Cause and Consequence of Metabolic Dysregulation in Aging Humans: Effects of Gut Dysbiosis, Glucose Dysregulation, Diet and Lifestyle”
by James W. Daily and Sunmin Park
Cells 2022, 11(3), 338; https://doi.org/10.3390/cells11030338
Available online: http://www.mdpi.com/2073-4409/11/3/338

“Roles of Podoplanin in Malignant Progression of Tumor”
by Hiroyuki Suzuki, Mika K. Kaneko and Yukinari Kato
Cells 2022, 11(3), 575; https://doi.org/10.3390/cells11030575
Available online: http://www.mdpi.com/2073-4409/11/3/575

“Skeletal Muscle Pathological Fat Infiltration (Myosteatosis) Is Associated with Higher Mortality in Patients with Cirrhosis”
by Maryam Ebadi, Cynthia Tsien, Rahima A. Bhanji, Abha R. Dunichand-Hoedl, Elora Rider, Maryam Motamedrad, Vera C. Mazurak, Vickie Baracos and Aldo J.Montano-Loza
Cells 2022, 11(8), 1345; https://doi.org/10.3390/cells11081345
Available online: http://www.mdpi.com/2073-4409/11/8/1345

“CFTR Modulators in People with Cystic Fibrosis: Real-World Evidence in France”
by Lucile Regard, Clemence Martin, Esperie Burnet, Jennifer Da Silva and Pierre-Regis Burgel
Cells 2022, 11(11), 1769; https://doi.org/10.3390/cells11111769
Available online: http://www.mdpi.com/2073-4409/11/11/1769

“Role of Immuno-Inflammatory Signals in Liver Ischemia-Reperfusion Injury”
by Christof Kaltenmeier, Ronghua Wang, Brandon Popp, David Geller, Samer Tohme and Hamza O. Yazdani
Cells 2022, 11(14), 2222; https://doi.org/10.3390/cells11142222
Available online: http://www.mdpi.com/2073-4409/11/14/2222

“Açaì Berry Mitigates Vascular Dementia-Induced Neuropathological Alterations Modulating Nrf-2/Beclin1 Pathways”
by Daniela Impellizzeri, Ramona D'Amico, Roberta Fusco, Tiziana Genovese, Alessio Filippo Peritore, Enrico Gugliandolo, Rosalia Crupi, Livia Interdonato, Davide Di Paola, Rosanna Di Paola et al.
Cells 2022, 11(16), 2616; https://doi.org/10.3390/cells11162616
Available online: http://www.mdpi.com/2073-4409/11/16/2616

“Sex Hormones, Growth Hormone, and the Cornea”
by Tina B. McKay, Shrestha Priyadarsini and Dimitrios Karamichos
Cells 2022, 11(2), 224; https://doi.org/10.3390/cells11020224
Available online: http://www.mdpi.com/2073-4409/11/2/224

“S-Adenosylmethionine: From the Discovery of Its Inhibition of Tumorigenesis to Its Use as a Therapeutic Agent”
by Rosa M. Pascale, Maria M. Simile, Diego F. Calvisi, Claudio F. Feo and Francesco Feo
Cells 2022, 11(3), 409; https://doi.org/10.3390/cells11030409
Available online: http://www.mdpi.com/2073-4409/11/3/409

“EGFR Signaling in Lung Fibrosis”
by Fabian Schramm, Liliana Schaefer and Malgorzata Wygrecka
Cells 2022, 11(6), 986; https://doi.org/10.3390/cells11060986
Available online: http://www.mdpi.com/2073-4409/11/6/986

“Oxidative Stress and Mitochondrial Dysfunction in Chronic Kidney Disease”
by Hsin-Jung Ho and Hitoshi Shirakawa
Cells 2023, 12(1), 88; https://doi.org/10.3390/cells12010088
Available online: http://www.mdpi.com/2073-4409/12/1/88

“Neuronal-Derived EV Biomarkers Track Cognitive Decline in Alzheimer’s Disease”
by Erden Eren, Jeannie-Marie Leoutsakos, Juan Troncoso, Constantine G. Lyketsos, Esther S. Oh and Dimitrios Kapogiannis
Cells 2022, 11(3), 436; https://doi.org/10.3390/cells11030436
Available online: http://www.mdpi.com/2073-4409/11/3/436

“Mechanisms of Cisplatin Resistance in HPV Negative Head and Neck Squamous Cell Carcinomas”
by Ana Belen Griso, Lucia Acero-Riaguas, Beatriz Castelo, Jose Luis Cebrian-Carretero and Ana Sastre-Perona
Cells 2022, 11(3), 561; https://doi.org/10.3390/cells11030561
Available online: http://www.mdpi.com/2073-4409/11/3/561

“Hashimoto Encephalopathy—Still More Questions than Answers”
by Marta Waliszewska-Prosot and Maria Ejma
Cells 2022, 11(18), 2873; https://doi.org/10.3390/cells11182873
Available online: http://www.mdpi.com/2073-4409/11/18/2873

“Role of the Tumor Microenvironment in Regulating Pancreatic Cancer Therapy Resistance”
by Daiyong Deng, Riya Patel, Cheng-Yao Chiang and Pingping Hou
Cells 2022, 11(19), 2952; https://doi.org/10.3390/cells11192952
Available online: http://www.mdpi.com/2073-4409/11/19/2952

“Carnosic Acid Attenuates the Free Fatty Acid-Induced Insulin Resistance in Muscle Cells and Adipocytes”
by Danja J. Den Hartogh, Filip Vlavcheski, Adria Giacca, Rebecca E. K. MacPherson and Evangelia Tsiani
Cells 2022, 11(1), 167; https://doi.org/10.3390/cells11010167
Available online: http://www.mdpi.com/2073-4409/11/1/167

“CFTR Modulator Therapies: Potential Impact on Airway Infections in Cystic Fibrosis”
by Francesca Saluzzo, Luca Riberi, Barbara Messore, Nicola Ivan Lore, Irene Esposito, Elisabetta Bignamini and Virginia De Rose
Cells 2022, 11(7), 1243; https://doi.org/10.3390/cells11071243
Available online: http://www.mdpi.com/2073-4409/11/7/1243

“Association of Oral Function and Dysphagia with Frailty and Sarcopenia in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis”
by Kotomi Sakai, Enri Nakayama, Daisuke Yoneoka, Nobuo Sakata, Katsuya lijima, Tomoki Tanaka, Kuniyoshi Hayashi, Kunihiro Sakuma and Eri Hoshino
Cells 2022, 11(14), 2199; https://doi.org/10.3390/cells11142199
Available online: http://www.mdpi.com/2073-4409/11/14/2199

“Serum of Post-COVID-19 Syndrome Patients with or without ME/CFS Differentially Affects Endothelial Cell Function In Vitro”
by Lavinia Flaskamp, Constanze Roubal, Steven Uddin, Franziska Sotzny, Claudia Kedor, Sandra Bauer, Carmen Scheibenbogen and Martina Seifert
Cells 2022, 11(15), 2376; https://doi.org/10.3390/cells11152376
Available online: http://www.mdpi.com/2073-4409/11/15/2376

“The Contribution of Lipotoxicity to Diabetic Kidney Disease”
by Jeffrey R. Schelling
Cells 2022, 11(20), 3236; https://doi.org/10.3390/cells11203236
Available online: http://www.mdpi.com/2073-4409/11/20/3236

“Micro-RNAs Shuttled by Extracellular Vesicles Secreted from Mesenchymal Stem Cells Dampen Astrocyte Pathological Activation and Support Neuroprotection in In-Vitro Models of ALS”
by Francesca Provenzano, Sophie Nyberg, Debora Giunti, Carola Torazza, Benedetta Parodi, Tiziana Bonifacino, Cesare Usai, Nicole Kerlero de Rosbo, Marco Milanese, Antonio Uccelli et al.
Cells 2022, 11(23), 3923; https://doi.org/10.3390/cells11233923
Available online: http://www.mdpi.com/2073-4409/11/23/3923

“Immunity and Nutrition: The Right Balance in Inflammatory Bowel Disease”
by Bartolo Tamburini, Marco Pio La Manna, Lidia La Barbera, Leila Mohammadnezhad, Giusto Davide Badami, Mojtaba Shekarkar Azgomi, Francesco Dieli and Nadia Caccamo
Cells 2022, 11(3), 455; https://doi.org/10.3390/cells11030455
Available online: http://www.mdpi.com/2073-4409/11/3/455

“Antibody-Drug Conjugates in Urothelial Carcinoma: A New Therapeutic Opportunity Moves from Bench to Bedside”
by Antonio Ungaro, Marcello Tucci, Alessandro Audisio, Lavinia Di Prima, Chiara Pisano, Fabio Turco, Marco Donatello Delcuratolo, Massimo Di Maio, Giorgio Vittorio Scagliotti and Consuelo Buttigliero
Cells 2022, 11(5), 803; https://doi.org/10.3390/cells11050803
Available online: http://www.mdpi.com/2073-4409/11/5/803

“Hsp90 in Human Diseases: Molecular Mechanisms to Therapeutic Approaches”
by Mamta P. Sumi and Arnab Ghosh
Cells 2022, 11(6), 976; https://doi.org/10.3390/cells11060976
Available online: http://www.mdpi.com/2073-4409/11/6/976

“Adaptive Remodeling of the Neuromuscular Junction with Aging”
by Michael R. Deschenes, Rachel Flannery, Alexis Hawbaker, Leah Patekand and Mia Mifsud
Cells 2022, 11(7), 1150; https://doi.org/10.3390/cells11071150
Available online: http://www.mdpi.com/2073-4409/11/7/1150

“Iron-Induced Oxidative Stress in Human Diseases”
by Teruyuki Kawabata
Cells 2022, 11(14), 2152; https://doi.org/10.3390/cells11142152
Available online: http://www.mdpi.com/2073-4409/11/14/2152

“Intraocular RGD-Engineered Exosomes and Active Targeting of Choroidal Neovascularization (CNV)”
by Dimitrios Pollalis, Dongin Kim, Gopa Kumar Gopinadhan Nair, Changsun Kang, Arjun V. Nanda and Sun Young Lee
Cells 2022, 11(16), 2573; https://doi.org/10.3390/cells11162573
Available online: http://www.mdpi.com/2073-4409/11/16/2573

“Role of Epigenetic Mechanisms in Chronic Pain”
by Daniela Mauceri
Cells 2022, 11(16), 2613; https://doi.org/10.3390/cells11162613
Available online: http://www.mdpi.com/2073-4409/11/16/2613

“PICALM and Alzheimer’s Disease: An Update and Perspectives”
by Kunie Ando, Siranjeevi Nagaraj, Fahri Kugukali, Marie-Ange de Fisenne, Andreea-Claudia Kosa, Emilie Doeraene, Lidia Lopez Gutierrez, Jean-Pierre Brion and Karelle Leroy
Cells 2022, 11(24), 3994; https://doi.org/10.3390/cells11243994
Available online: http://www.mdpi.com/2073-4409/11/24/3994

“The Cytokine Network in Colorectal Cancer: Implications for New Treatment Strategies”
by Heidi Braumuller, Bernhard Mauerer, Johanna Andris, Christopher Berlin, Thomas Wieder and Rebecca Kesselring
Cells 2023, 12(1), 138; https://doi.org/10.3390/cells12010138
Available online: http://www.mdpi.com/2073-4409/12/1/138

“Differential Discontinuation Profiles between Pirfenidone and Nintedanib in Patients with Idiopathic Pulmonary Fibrosis”
by Kazutaka Takehara, Yasuhiko Koga, Yoshimasa Hachisu, Mitsuyoshi Utsugi, Yuri Sawada, Yasuyuki Saito, Seishi Yoshimi, Masakiyo Yatomi, Yuki Shin, lkuo Wakamatsu et al.
Cells 2022, 11(1), 143; https://doi.org/10.3390/cells11010143
Available online: http://www.mdpi.com/2073-4409/11/1/143

“New Perspectives in the Medical Treatment of Non-Muscle-Invasive Bladder Cancer: Immune Checkpoint Inhibitors and Beyond”
by Alessandro Audisio, Consuelo Buttigliero, Marco Donatello Delcuratolo, Elena Parlagreco, Marco Audisio, Antonio Ungaro, Rosario Francesco Di Stefano, Lavinia Di Prima, Fabio Turco and Marcello Tucci
Cells 2022, 11(3), 357; https://doi.org/10.3390/cells11030357
Available online: http://www.mdpi.com/2073-4409/11/3/357

“Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?”
by Anna Zakrzewicz, Celina Wurth, Benedikt Beckert, Simon Feldhoff, Katrien Vanderheyden, Stian Foss, Jan Terje Andersen, Hans de Haard, Peter Verheesen and Vladimir Bobkov
Cells 2022, 11(6), 942; https://doi.org/10.3390/cells11060942
Available online: http://www.mdpi.com/2073-4409/11/6/942

“The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox”
by Marie Claes, Lies De Groef and Lieve Moons
Cells 2022, 11(7), 1110; https://doi.org/10.3390/cells11071110
Available online: http://www.mdpi.com/2073-4409/11/7/1110

“Selected Methods of Resistance Training for Prevention and Treatment of Sarcopenia”
by Tomohiro Yasuda
Cells 2022, 11(9), 1389; https://doi.org/10.3390/cells11091389
Available online: http://www.mdpi.com/2073-4409/11/9/1389

“Loss of Proximal Tubular Sirtuin 6 Aggravates Unilateral Ureteral Obstruction-Induced Tubulointerstitial Inflammation and Fibrosis by Regulation of β-Catenin Acetylation”
by Jixiu Jin, Wenjia Li, Tian Wang, Byung-Hyun Park, Sung Kwang Park and Kyung Pyo Kang
Cells 2022, 11(9), 1477; https://doi.org/10.3390/cells11091477
Available online: http://www.mdpi.com/2073-4409/11/9/1477

“Programmed Cell Death-1/Programmed Cell Death-1 Ligand as Prognostic Markers of Coronavirus Disease 2019 Severity”
by Paulina Niedzwiedzka-Rystwej, Adam Majchrzak, Bogusz Aksak-Wąs, Karol Serwin, Zenon Czajkowski, Ewelina Grywalska, lzabela Korona-Glowniak, Jacek Rolifiski and Mitosz Parczewski
Cells 2022, 11(12), 1978; https://doi.org/10.3390/cells11121978
Available online: http://www.mdpi.com/2073-4409/11/12/1978

“Structural Aspects of LIMK Regulation and Pharmacology”
by Deep Chatterjee, Franziska Preuss, Verena Dederer, Stefan Knapp and Sebastian Mathea
Cells 2022, 11(1), 142; https://doi.org/10.3390/cells11010142
Available online: http://www.mdpi.com/2073-4409/11/1/142

“Adoptive Cellular Therapy for Multiple Myeloma Using CAR- and TCR-Transgenic T Cells: Response and Resistance”
by Franziska Fuchsl and Angela M. Krackhardt
Cells 2022, 11(3), 410; https://doi.org/10.3390/cells11030410
Available online: http://www.mdpi.com/2073-4409/11/3/410

“Combining HDAC and MEK Inhibitors with Radiation against Glioblastoma-Derived Spheres”
by Eno I. Essien, Thomas P. Hofer, Michael J. Atkinson and Nataša Anastasov
Cells 2022, 11(5), 775; https://doi.org/10.3390/cells11050775
Available online: http://www.mdpi.com/2073-4409/11/5/775

“Stevioside Enhances the Anti-Adipogenic Effect and β-Oxidation by Activating AMPK in 3T3-L1 Cells and Epididymal Adipose Tissues of db/db Mice”
by Miey Park, Hana Baek, Jin-Young Han and Hae-Jeung Lee
Cells 2022, 11(7), 1076; https://doi.org/10.3390/cells11071076
Available online: http://www.mdpi.com/2073-4409/11/7/1076