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Receptors, Volume 4, Issue 2

June 2025 - 4 articles

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Review

2,054 Views

15 Pages

Odorant Receptors and Cancer

Rafaella G. Naressi,
Bettina Malnic and
Luciana M. Gutiyama

Receptors2025, 4(2), 11;https://doi.org/10.3390/receptors4020011

9 June 2025

Odorant receptors (ORs) constitute the largest family of G protein-coupled receptors (GPCRs), with nearly 400 receptors identified in humans. The “omics” era has revealed an unexpected expression of ORs beyond olfactory tissues. For many...

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Article

1,155 Views

16 Pages

Gelsolin Facilitates Estrogen Receptor Beta Nuclear Translocation and Transcriptional Repression of Genes Associated with Alzheimer Disease

Yoldas Yildiz,
Angela H. S. Fan,
Amanda A. Hartoun,
Sarah Flury,
Yan Ngai and
Toni R. Pak

Receptors2025, 4(2), 10;https://doi.org/10.3390/receptors4020010

1 May 2025

Background/Objectives: Gelsolin (GSN) is an actin-binding protein that helps maintain neuronal structure and shape, regulates neuronal growth, and apoptosis. Our previous work demonstrated that GSN associated with estrogen receptor beta (ERβ1) i...

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Review

4,569 Views

19 Pages

Bioelectric Membrane Potential and Breast Cancer: Advances in Neuroreceptor Pharmacology for Targeted Therapeutic Strategies

Chitaranjan Mahapatra,
Jineetkumar Gawad,
Chandrakant Bonde and
Mahesh B. Palkar

Receptors2025, 4(2), 9;https://doi.org/10.3390/receptors4020009

2 April 2025

Bioelectric membrane potentials regulate cellular growth, differentiation, and movement. Disruptions in bioelectric signaling are strongly linked to cancer development, as abnormal membrane potentials and ion channel activity can drive tumor progress...

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Perspective

1,545 Views

9 Pages

Role of Glucocorticoid Receptor in Triple-Negative Breast Cancer

Raj Kumar

Receptors2025, 4(2), 8;https://doi.org/10.3390/receptors4020008

1 April 2025

Triple-negative breast cancer (TNBC) is an aggressive tumor among breast cancer subtypes with much lower overall survival at metastasis compared to other subtypes and with limited treatment options due to a lack of targeted therapies. This has led to...

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Receptors - ISSN 2813-2564

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