IECC 2023 2023 - 9 articles
Online | 16–30 March 2023
Volume Editors:
Carlos Moreno, Emory University School of Medicine, USA
Nicola Amodio, Magna Graecia University of Catanzaro, Italy
Glioblastoma multiforme (GBM) is the most common aggressive malignant primary brain tumor, afflicting approximately 3.19 per 100,000 persons in the United States with an incidence 1.6 times higher in males compared to females. Arising from the glial...
Cinnamon extract has received significant attention due to its significant antibacterial, antifungal, antioxidant, and even anti-cancer properties. The purpose of this study was to create cinnamon-extract-loaded PLGA nanoparticles and evaluate their...
Molecular aberrations in endometriosis were known to be associated with an increased risk of epithelial ovarian cancer (EOCs), especially endometrioid ovarian cancer (EnOC) and ovarian clear cell carcinoma (OCCC). Causal genetic evidence currently re...
A total of 30% of lung adenocarcinoma are driven by activating KRAS mutations. The treatment options for KRAS-mutant lung cancer are still limited as a challenge for therapy is the high heterogeneity within KRAS mutant tumors. Co-existing genetic eve...
More than 650,000 people die each year from breast cancer, making it a particularly significant disease worldwide. The development of about 70% of breast tumors depends on steroid hormones, namely, estrogens. Estrogens trigger signaling pathways that...
The rearrangement of molecular pathways and the activation of bypass signaling determine the progression of tumor cell resistance to various drugs that specifically block target signaling proteins. The present work was performed on the MCF-7 breast c...
A promising strategy to enhance the therapeutic effectiveness for the treatment of oncological diseases involves the development of combined therapeutic schemes. In our work, we showed the therapeutic potential of the combined action of the anticance...
Runt-related transcription factor 1 gene (RUNX1), also known as acute myeloid leukaemia 1 protein (AML1), plays a crucial role in the pathogenesis of AML. RUNX1/AML1 is one of the most frequently mutated leukaemias associated with a poor prognosis in...
Genetic alterations in the NFE2L2 gene have been identified across various cancers, and the dysregulation of the NRF2 pathway due to these alterations leads to drug and radioresistance in several cancers. Identification of biomarkers associated with...
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