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BioChem, Volume 2, Issue 3

September 2022 - 3 articles

Cover Story: Protein-template-assisted synthesis of artificial metalloenzymes is a promising and ever-expanding scope of bio-inorganic chemistry. Over the decades, designed biocatalysts are useful for the synthesis of various molecules for pharmaceutical, biotechnological, and industrial purposes. Therefore, metalloenzymes are the relevant targets for the design of artificial biocatalysts. The search and development of new scaffolds capable of hosting metals with high levels of selectivity could significantly expand the scope of biocatalysis. This review highlights three protein scaffolds (rubredoxin, ferredoxin and orange protein) for designing models for complex enzymes such as hydrogenase and carbon monoxide dehydrogenase, and also useful as spectroscopic probes. View this paper
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Articles (3)

  • Review
  • Open Access
26 Citations
14,480 Views
17 Pages

Testicular Glycogen Metabolism: An Overlooked Source of Energy for Spermatogenesis?

  • Ricardo Silva,
  • David F. Carrageta,
  • Marco G. Alves and
  • Pedro F. Oliveira

6 September 2022

The incidence of male infertility has been increasing over the years and is now becoming a serious health problem. This trend has been followed by an increase in metabolic diseases, which are known to induce clear alterations in testicular metabolism...

  • Review
  • Open Access
3 Citations
4,478 Views
16 Pages

1 August 2022

Metalloenzymes are the most proficient nature catalysts that are responsible for diverse biochemical transformations introducing excellent selectivity and performing at high rates, using intricate mutual relationships between metal ions and proteins....

  • Review
  • Open Access
4,053 Views
11 Pages

4 July 2022

Three forms of methylated cytosines are present in the eukaryotic genome: 3-methylcytosine, 4-methylcytosine and 5-methylcytosine. 3-methylcytosines create methyl lesions, which impair local DNA function and flexibility, resulting in replication and...

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BioChem - ISSN 2673-6411