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Gastrointestinal Disorders, Volume 7, Issue 2

June 2025 - 15 articles

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Articles (15)

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Article

2,137 Views

16 Pages

Whole-Exome Sequencing Identified Molecular Variants Linked to the Progression of Gastric Precancerous Lesions in Patients from Southwestern Colombia—An Exploratory Approach

Lizeth Mejia-Ortiz,
Jovanny Zabaleta,
Jone Garai,
Luis Eduardo Bravo and
Andres Castillo

Gastrointest. Disord.2025, 7(2), 30;https://doi.org/10.3390/gidisord7020030

25 April 2025

Background/Objectives: This study aimed to identify molecular variants associated with the progression of gastric precancerous lesions in a follow-up study conducted on patients from Southwestern Colombia. Methods: Whole-exome sequencing (WES) was pe...

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Article

1 Citations

3,368 Views

13 Pages

Endoscopic Suturing for Defect Closure in the Upper Gastrointestinal Tract: A Retrospective Cohort Study

Apostolis Papaefthymiou,
Nasar Aslam,
Benjamin Norton,
Andrea Telese,
Charles Murray,
Alberto Murino,
Gavin Johnson,
Roberto Simons-Linares and
Rehan Haidry

Gastrointest. Disord.2025, 7(2), 29;https://doi.org/10.3390/gidisord7020029

23 April 2025

Background: The increasing availability of gastrointestinal (GI) interventions has raised the need to treat luminal defects. Endoscopic suturing (ES) is a minimally invasive technique that is used for a wide range of indications. This retrospective c...

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Review

7 Citations

4,816 Views

26 Pages

Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases

Ana Jagodic,
Antea Krsek,
Lou Marie Salomé Schleicher and
Lara Baticic

Gastrointest. Disord.2025, 7(2), 28;https://doi.org/10.3390/gidisord7020028

2 April 2025

Microbiome dysbiosis—an imbalance in gut microbial communities—has emerged as a critical factor in the pathogenesis of neurological disorders, particularly Alzheimer’s and Parkinson’s diseases. This review examines the role of...

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Review

2 Citations

2,057 Views

12 Pages

Single Anastomosis Duodenoileostomy with Sleeve Gastrectomy Versus Sleeve Gastrectomy Alone: A Systematic Review and Meta-Analysis on Behalf of TROGSS—The Robotic Global Surgical Society

Yeisson Rivero-Moreno,
Alba Zevallos,
Samantha Redden-Chirinos,
Víctor Bolivar-Marín,
Dayanna Silva-Martinez,
Aman Goyal,
Arturo Estrada,
Rebeca Domínguez-Profeta,
Diego Camacho and
Sjaak Pouwels
+ 4 authors

Gastrointest. Disord.2025, 7(2), 27;https://doi.org/10.3390/gidisord7020027

26 March 2025

Background: Single-Anastomosis Duodenoileostomy with Sleeve Gastrectomy (SADI-S) has been reported as both a safe and effective surgical procedure. However, these findings have not been directly compared to those of more established and less complex...

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Article

4 Citations

3,553 Views

20 Pages

Development and Internal Validation of a Machine Learning-Based Colorectal Cancer Risk Prediction Model

Deborah Jael Herrera,
Daiane Maria Seibert,
Karen Feyen,
Marlon van Loo,
Guido Van Hal and
Wessel van de Veerdonk

Gastrointest. Disord.2025, 7(2), 26;https://doi.org/10.3390/gidisord7020026

24 March 2025

Background: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide. While screening tools such as the fecal immunochemical test (FIT) aid in early detection, they do not provide insights into individual risk factors or...

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