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Gastrointestinal Disorders, Volume 8, Issue 2

2026 June - 15 articles

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Articles (15)

  • Systematic Review
  • Open Access
894 Views
12 Pages

Daytime Napping and Liver Cancer Risk: A Systematic Review and Meta-Analysis of Prospective Cohort Studies

  • Ahmed Arafa,
  • Amira S. A. Said,
  • Tarig A. Y. Ali,
  • Ehab Elkady and
  • Doaa Mahmoud Khalil

Background: Liver cancer is a major global public health challenge, with substantial morbidity, mortality, and economic costs. Growing attention has turned to sleep-related behaviors, including daytime napping, as potential risk factors for cancer. E...

(This article belongs to the Special Issue Feature Papers in Gastrointestinal Disorders in 2025–2026)
  • Article
  • Open Access
1,061 Views
19 Pages

Background/Objectives: Tordylium trachycarpum Boiss. (Apiaceae) is traditionally used in Kurdish ethnomedicine for the management of gastrointestinal disorders; however, its pharmacological efficacy and safety profile remain insufficiently investigat...

  • Review
  • Open Access
947 Views
13 Pages

Statins for Primary Prevention of Variceal Bleeding in Cirrhosis: A Scoping Review

  • Jonah C. Short-Miller,
  • Michelle Rhea,
  • Jay Jamieson,
  • Alyson Smith and
  • Jason Brumitt

Background/Objectives: Variceal bleeding (VB) is a major complication of cirrhosis, marking a progression from a compensated to a decompensated stage of the disease. Previous research has suggested that HMG-CoA reductase inhibitors, commonly called s...

  • Article
  • Open Access
1,104 Views
18 Pages

Trends, Predictors, and Outcomes of 30- and 90-Day Readmissions Following Alcoholic Hepatitis: A Nationwide Readmissions Database Study, 2016–2022

  • Saksham Kohli,
  • Anil Philip,
  • Yetunde Akande,
  • Philip Sarpong-Mensah,
  • Ibrahimkhalil-Mohamud Ibrahim Sheikh,
  • Lina George,
  • Jhalak Agrohi and
  • Hemant Mutneja

Background: Alcoholic hepatitis (AH) is associated with high short-term morbidity and mortality, but contemporary national data on hospital readmissions remain limited. Methods: Using the Nationwide Readmissions Database (2016–2022), we identif...

(This article belongs to the Special Issue Diagnosis and Treatment of Digestive Diseases: Emerging Mechanisms and Systemic Complications)
  • Review
  • Open Access
3 Citations
1,414 Views
14 Pages

Rethinking Colorectal Cancer Microbiome: From Universal Biomarkers to Patient-Stratified Signatures

  • Carlo Alberto Schena,
  • Vito Laterza,
  • Marcello Covino and
  • Fausto Rosa

The gut microbiome has emerged as one of the most promising sources of non-invasive biomarkers for colorectal cancer (CRC). Over the past decade, fecal metagenomic studies have consistently identified a core CRC-associated signature enriched with ora...

  • Review
  • Open Access
1,276 Views
15 Pages

Minimally Invasive Pancreas-Preserving Duodenal Resections: Indications, Technical Strategies, and Outcomes

  • Mario Annecchiarico,
  • Giuseppe Loiaco,
  • Claudia Cirillo,
  • Antonio Antonino,
  • Giulio Argenio,
  • Angela Romano,
  • Antonio Varricchio,
  • Francesco Carafa,
  • Pellegrino Gambardella and
  • Giuseppe Palomba
  • + 1 author

Minimally invasive pancreas-preserving duodenal resection (MIPPDR) encompasses laparoscopic, robotic, and intentionally hybrid duodenal resections performed without pancreatic parenchymal excision, ranging from transduodenal local excision or ampulle...

(This article belongs to the Special Issue Minimally Invasive Surgery for Upper Gastrointestinal Tract Diseases: New Trends and Future Perspectives)
  • Review
  • Open Access
2 Citations
3,153 Views
26 Pages

Intestinal Barrier: Mechanisms of Disruption and Strategies for Restoration in Ulcerative Colitis

  • Mei-Na Wang,
  • Chuan-Guo Liu,
  • Jia Pan,
  • Xiao-Gang Pang and
  • Hui-Min Liu

Background: Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease. Intestinal barrier impairment represents a core pathogenic mechanism and a key therapeutic target for achieving mucosal healing and sustained remission. Methods: T...

(This article belongs to the Topic Advances in Comprehensive Management Strategies for Inflammatory Bowel Disease)
  • Systematic Review
  • Open Access
1,318 Views
15 Pages

Artificial Intelligence in Helicobacter Pylori Infection: Diagnostic Applications and Emerging Treatment-Related Predictive Uses—A Systematic Review

  • Esteban Zavaleta-Monestel,
  • Yennifer Villagra-Hernandez,
  • Jeaustin Mora-Jiménez,
  • Jorge Arturo Villalobos-Madriz,
  • Carolina Rojas-Chinchilla,
  • José Andrés Castro-Gamboa,
  • Luis Guillermo Herrera-Jiménez,
  • Sebastián Arguedas-Chacón and
  • Christian Campos-Núñez

Background: Artificial intelligence (AI) has shown growing potential in the diagnosis of H. pylori infection, particularly through automated analysis of endoscopic images. Emerging studies have also explored treatment-related predictive applications,...

  • Article
  • Open Access
1,577 Views
17 Pages

The Intestinal Microbiota Profile of Patients with Colon Cancer in Southern Peru: An Exploratory Regional Analysis

  • Ángel Mamani-Ruelas,
  • Jani Pacheco-Aranibar,
  • Johany Sánchez Guillen,
  • Gladys Núñez-Zevallos,
  • Jhony R. Rodríguez Mamani,
  • Francis W. Jacobo-Valdivia,
  • Carlos Gámez-Bernabe,
  • Steven Criollo-Arteaga,
  • Eusebio Walter Colque Rondon and
  • Julio Cesar Bernabe-Ortiz

Background/Objectives: Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. Emerging evidence highlights the role of the gut microbiota in the development and progression of CRC. Microbial dysbiosis is hypothesized to con...

  • Article
  • Open Access
1,427 Views
11 Pages

Diagnostic Revision and Organic Disease Risk in Pediatric Rome IV Disorders of Gut–Brain Interaction: A Single-Center Retrospective Cohort

  • Silvia Caimmi,
  • Amelia Licari,
  • Alice Di Carlo,
  • Giulia Fusi,
  • Gianluigi Marseglia and
  • Mirko Bertozzi

Background: Rome IV criteria promote a symptom-based (“positive”) diagnosis of pediatric disorders of gut–brain interaction (DGBIs). In clinical practice, however, organic gastrointestinal diseases may mimic DGBIs and lead to diagno...

  • Review
  • Open Access
2,913 Views
18 Pages

Autoimmune Hepatitis: Emerging Frontiers in Research and Clinical Management

  • Armando Curto,
  • Irene Scami,
  • Giulia Gliottone,
  • Rocco G. Iamello,
  • Erica N. Lynch and
  • Andrea Galli

Autoimmune hepatitis (AIH) is a chronic immune-mediated liver disorder that, without treatment, can advance to fibrosis and cirrhosis. Although standard regimens with corticosteroids and thiopurines have significantly improved survival, many patients...

(This article belongs to the Special Issue Feature Papers in Gastrointestinal Disorders in 2025–2026)
  • Article
  • Open Access
1,108 Views
8 Pages

Assessing Antimicrobial Stewardship in Paediatric Clostridioides difficile Positivity: To Treat or Not to Treat?

  • Federico Motta,
  • Silvia Marino,
  • Patrizia Grassi,
  • Alessia Migliore,
  • Salvatore Leonardi,
  • Giovanna Russo and
  • Milena La Spina

Background: Molecular syndromic stool panels are increasingly used in paediatric diarrheal syndromes; however, interpretation of Clostridioides difficile (C. difficile) detection remains challenging because colonisation is common in younger children....

  • Article
  • Open Access
1,507 Views
10 Pages

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract (GIT). This study aims to report the experience in the surgical treatment of GIST patients, evaluate the prognostic factors and d...

  • Article
  • Open Access
1,074 Views
9 Pages

A Real-Life Evaluation of the Best Bowel Preparation Regimen Identified in the PrepRICE Trial for Capsule Endoscopies

  • Catarina Costa,
  • Maria Manuela Estevinho,
  • Pedro Mesquita,
  • Rita Ferreira,
  • Pedro Vilela Teixeira,
  • João Santos,
  • Ana Ponte and
  • Rolando Pinho

Background: The optimal bowel preparation regimen for a small bowel capsule endoscopy (SBCE) remains uncertain. The PrepRICE clinical trial showed that the administration of purgatives after the capsule reached the duodenum improved the mucosal visua...

(This article belongs to the Topic Evolving Role of Endoscopy in Adult and Pediatric Gastrointestinal Disorders)
  • Case Report
  • Open Access
2,057 Views
23 Pages

Laparoscopic Cholecystectomy In Situs Viscerum Inversus Totalis: The Role of Indocyanine Green Fluorescence—A Case Report of Kartagener Syndrome and Narrative Review

  • Agostino Fernicola,
  • Giuseppe Scognamiglio,
  • Viviana Verlingieri,
  • Luigi Ricciardelli,
  • Andrea Paolillo,
  • Veronika Dadaev,
  • Moshe Argaman,
  • Yael Ben Avraham,
  • Felice Crocetto and
  • Fahim Kanani
  • + 3 authors

Background: Kartagener syndrome (KS) is a rare subset of primary ciliary dyskinesia characterized by the triad of situs viscerum inversus (SVI), chronic sinusitis, and bronchiectasis. Laparoscopic cholecystectomy (LC) in patients with SVI is technica...

(This article belongs to the Special Issue GastrointestinaI & Bariatric Surgery)
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Gastrointest. Disord. - ISSN 2624-5647